Tactile roughness discrimination of the finger pad relies primarily on vibration sensitive afferents not necessarily located in the hand
Tactile roughness discrimination of the finger pad relies primarily on vibration sensitive afferents not necessarily located in the hand
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DOI：
10.1016/j.bbr.2012.01.018
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发表时间：
2012-04-01
影响因子：
2.7
通讯作者：
Thonnard, Jean-Louis
中科院分区：
文献类型：
--
作者：
Libouton, Xavier;Barbier, Olivier;Thonnard, Jean-Louis
本研究旨在探讨远端机械感受器对粗糙度和空间敏锐度感知的相对贡献。我们检查了两种影响食指不同神经支配的单侧病理条件：单侧腕管综合征（n = 12）和手术修复后腕部完全创伤正中神经切断（n = 4）。我们采用了一个控制条件，包括环阻滞麻醉的整个指数在10名健康受试者的病理性去神经支配的指尖。空间敏锐度和辨别粗糙度的能力分别使用光栅定向任务和粗糙度辨别任务进行评估。我们观察到空间分辨敏锐度显著降低，但用指尖辨别粗糙度的能力完好无损，对于创伤性正中神经切断的患者，术后20个月光栅定向任务没有恢复，在6至9个月的粗糙度辨别任务中，逐渐完全恢复。最后，在麻醉环阻滞组中，神经阻滞完全破坏了光栅定向任务的表现，但意外地留下了不受影响的表现在粗糙度discriminationtask.Taken在一起，这些线的证据支持的观点，触觉粗糙度歧视的神经机制不同的空间分辨率的敏锐度。振动是必要的和足够的感知精细的纹理，当神经支配的指垫是妥协，纹理的信息可以被捕获和编码的远程mechanoreceptors位于更近端的组织，其中神经支配是完整的。(C)2012爱思唯尔有限公司版权所有。
This study aims to investigate the relative contribution of remote mechanoreceptors to perception of roughness and spatial acuity. We examined two unilateral pathological conditions affecting differently innervation of the index finger: unilateral carpal tunnel syndrome (n = 12) and surgically repaired complete traumatic median nerve section at the wrist following surgical repair (n = 4). We employed a control condition consisting of ring-block anesthesia of the entire index in 10 healthy subjects to model pathological denervation of the fingertip. Spatial acuity and the ability to discern roughness were assessed using a grating orientation task and a roughness discrimination task, respectively.In patients with carpal tunnel syndrome, we observed a significant reduction of spatial resolution acuity but an intact ability to discriminate roughness with the fingertip.For patients with traumatic median nerve section there was no recovery with the grating orientation task up to 20 months post surgery but a progressive and full recovery with the roughness discrimination task between 6 and 9 months. Finally, in the anesthetic ring bloc group, the nerve block completely disrupted performances in grating orientation task, but unexpectedly left unaffected performances in the roughness discrimination task.Taken together, these lines of evidence support the view that the neural mechanisms underlying tactile roughness discrimination differ from those involved in spatial resolution acuity. Vibrotaction is necessary and sufficient for the perception of fine textures and, when the innervation of the fingerpad is compromised, information about textures can be captured and encoded by remote mechanoreceptors located in more proximal tissues where the innervation is intact. (C) 2012 Elsevier B.V. All rights reserved.