Laser Doppler imaging and capillary microscopy in ischemic ulcers

Laser Doppler imaging and capillary microscopy in ischemic ulcers
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DOI:
10.1016/s0021-9150(98)00208-1
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发表时间:
1999-01-01
期刊:
影响因子:
5.3
通讯作者:
Ehringer, H
Ehringer, H
中科院分区:
医学2区
文献类型:
--
作者:
Gschwandtner, ME;Ambrózy, E;Ehringer, H

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对25例缺血性小腿溃疡及其邻近皮肤的局部激光多普勒血流分布(主要是温控灌流)和毛细血管密度(营养循环)进行了研究。为此,应用了激光多普勒成像技术和毛细管显微镜技术。在每个溃疡中,定义了非肉芽组织区(NGTA)、肉芽组织区(GTA)和邻近皮肤的皮肤区(SA)。在这些区域,每个患者的平均激光多普勒面积流量(AU)和毛细血管数/毫米(2)被测定。激光多普勒血流量的平均+/-S.D.分别为:NGTA 1.30+/-1.93,GTA 2.13+/-1.53和SA 1.21+/-0.77AU。GTA与NGTA或SA之间的差异有统计学意义(P
The local distribution of laser Doppler flu (mainly thermoregulatory perfusion) and capillary density (nutritive circulation) within 25 ischemic leg ulcers and their adjacent skin were investigated. For this purpose the technique of laser Doppler imaging and capillary microscopy were applied. In each ulcer a non granulation tissue area (NGTA), a granulation tissue area (GTA) and in adjacent skin a skin area (SA) were defined. In these areas the average laser Doppler area flux (arbitrary units, AU) and the number of capillaries/mm(2) were determined for each patient. The mean +/- S.D. of laser Doppler area fluxes were: NGTA 1.30 +/- 1.93, GTA 2.13 +/- 1.53 and SA 1.21 +/- 0.77 AU, respectively. The differences between GTA and NGTA or SA was statistically significant (p