Neurologic disorder of vitamin E deficiency in acquired intestinal malabsorption
Neurologic disorder of vitamin E deficiency in acquired intestinal malabsorption
复制标题
维生素 E 缺乏导致获得性肠道吸收不良的神经系统疾病
作者：
B. Weder;O. Meienberg;Erwin Wildi;Claus Meier
一位49岁的男性在吸收不良综合征发病15年后出现感觉和视觉障碍，并伴有明显的维生素E缺乏。经6个月高剂量维生素E治疗后，神经系统症状缓慢消退，但患者死于消化道出血。尸检和腓肠神经活检显示中枢和外周神经的变化;这些变化被认为是维生素E缺乏的特征。
Fifteen years after onset of a malabsorption syndrome a 49-year-old man had sensory and ocuolomotor disorder with marked vitamin E deficiency. After 6 months of treatment with high parenteral doses of vitamin E, the neurologic signs slowly receded, but the patient died of gastrointestinal hemorrhage. Autopsy and sural nerve biopsy showed the changes in both central and peripheral nerves; these changes are considered characteristic of vitamin E deficiency.