AN ASSESSMENT OF VERBAL RECALL, RECOGNITION AND FLUENCY ABILITIES IN PATIENTS WITH HUNTINGTONS-DISEASE
AN ASSESSMENT OF VERBAL RECALL, RECOGNITION AND FLUENCY ABILITIES IN PATIENTS WITH HUNTINGTONS-DISEASE
复制标题
DOI：
10.1016/s0010-9452(86)80030-2
复制
发表时间：
1986-03-01
期刊：
影响因子：
3.6
通讯作者：
MARTONE, M
中科院分区：
文献类型：
--
作者：
BUTTERS, N;WOLFE, J;MARTONE, M
进行了两项有关亨廷顿病 (HD) 患者记忆缺陷的研究。在第一个实验中，早期和晚期 HD 患者在雷伊听觉言语学习测试的改良回忆和识别形式上表现出比酗酒的科尔萨科夫患者更好的识别记忆。相比之下，在要求患者搜索语义记忆的字母流利度测试（FAS）中，HD 组产生的正确单词和坚持错误比酗酒的 Korsakoff 组要少。在第二个实验中，比较了 HD 患者和 Korsakoff 患者对短段落的识别能力。虽然 HD 和 Korsakoff 患者在回忆测试中受到同样的损害，但 HD 患者的识别记忆明显优于健忘症组。与流畅性测试一样，科尔萨科夫患者的散文的特点是侵入性（即持续性）错误。这两个实验的结果表明，HD 和 Korsakoff 患者的记忆缺陷分别与检索缺陷和对主动干扰的敏感性增加有关。
Two investigations concerned with the memory deficits of patients with Huntington''s disease (HD) were performed. In the first experiment, early and advanced HD patients showed superior recognition memory than did alcoholic Korsakoff patients on modified recall and recognition forms of the Rey Auditory Verbal Learning Test. In contrast, on a letter fluency test (FAS) requiring the patients to search their semantic memories, both HD groups produced fewer correct words and perseveration errors than did the alcoholic Korsakoff group. In the second experiment, HD patients and Korsakoff patients were compared in their and recognition of short passages. While the HD and Korsakoff patients were equally impaired on recall tests, the HD patients evidenced significantly better recognition memory than did the amnesic group. As on the fluency test, the prose of the Korsakoff patients was characterized by intrusion (i.e., perseverative) errors. The results of the two experiments indicate that HD and Korsakoff patients'' memory deficits are related to deficiencies in retrieval and an increased sensitivity to proactive interference, respectively.