The UCSC Genome Browser database: 2015 update.

The UCSC Genome Browser database: 2015 update.
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DOI:
10.1093/nar/gku1177
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发表时间:
2015-01
影响因子:
14.9
通讯作者:
Kent WJ
Kent WJ
中科院分区:
生物学2区
文献类型:
--
作者:
Rosenbloom KR;Armstrong J;Barber GP;Casper J;Clawson H;Diekhans M;Dreszer TR;Fujita PA;Guruvadoo L;Haeussler M;Harte RA;Heitner S;Hickey G;Hinrichs AS;Hubley R;Karolchik D;Learned K;Lee BT;Li CH;Miga KH;Nguyen N;Paten B;Raney BJ;Smit AF;Speir ML;Zweig AS;Haussler D;Kuhn RM;Kent WJ

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UCSC基因组浏览器数据库(http://www.example.com)于2001年启动,旨在展示人类基因组组装草图,该数据库和相关工具不断发展,为全世界的科学家和学生提供了基因组组装和注释的综合资源。genome.ucsc.edu过去一年的亮点包括在2013年12月发布了4年来第一个新的人类基因组参考汇编的浏览器(GRCh38,UCSC hg38),一个分水岭比较基因组学注释(100个物种的多重比对和保护)和一个新的浏览器分发机制(GBiB:盒子里的基因组浏览器)。我们为新物种(中国仓鼠、象鲨、小须鲸)创建了浏览器,为DNA序列“挖掘网络”,并通过堆叠彩色图表和区域突出显示来扩展浏览器显示。随着我们的用户社区越来越多地采用UCSC跟踪中心和组装中心表示来共享大规模基因组注释数据集和基因组测序项目,我们的公共数据中心菜单增加了两倍。
Launched in 2001 to showcase the draft human genome assembly, the UCSC Genome Browser database (http://genome.ucsc.edu) and associated tools continue to grow, providing a comprehensive resource of genome assemblies and annotations to scientists and students worldwide. Highlights of the past year include the release of a browser for the first new human genome reference assembly in 4 years in December 2013 (GRCh38, UCSC hg38), a watershed comparative genomics annotation (100-species multiple alignment and conservation) and a novel distribution mechanism for the browser (GBiB: Genome Browser in a Box). We created browsers for new species (Chinese hamster, elephant shark, minke whale), ‘mined the web’ for DNA sequences and expanded the browser display with stacked color graphs and region highlighting. As our user community increasingly adopts the UCSC track hub and assembly hub representations for sharing large-scale genomic annotation data sets and genome sequencing projects, our menu of public data hubs has tripled.
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发表时间: 2013-05-15
期刊: BIOINFORMATICS
影响因子: 5.8
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发表时间: 2011-04-01
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来自1,092个人基因组的遗传变异的综合图。
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发表时间: 2012-11-01
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DOI: 10.1101/gr.135350.111
发表时间: 2012-09
期刊: Genome research
影响因子: 7
作者:
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