Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan
Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan
复制标题
DOI：
10.1016/j.jep.2014.06.012
复制
发表时间：
2014-08-08
影响因子：
5.4
通讯作者：
Lin, Ching-Heng
中科院分区：
文献类型：
--
作者：
Chao, Te-Hsin;Fu, Pin-Kuei;Lin, Ching-Heng
民族药理学相关性：癌症患者通常使用中药，但台湾的中药处方模式尚不清楚。本研究旨在评估台湾地区大肠癌术后患者中药产品的使用情况，并探讨中药的使用模式。分析了中药治疗结肠癌的处方模式及原因。结果：结果显示，“症状、体征及不明情况”（23.3%）和消化系统疾病（16.9%）是使用中草药最常见的原因。香沙流君子汤（7.1%）、补中益气汤（4.3%）、加味消丸散（4.1%）、参灵百珠散（3.7%）、板下泻心汤（3.4%）、桂皮汤（2.4%）、平胃散（2.4%）、甘露饮（2.0%）、保和丸（1.9%）、镇人火明饮（1.8%）是结肠癌患者术后最常用的单一中药方剂。白花蛇舍草（5.1%）和半条莲（4.8%）是最常见的单一中药。结论：本研究发现台湾地区大肠癌术后中药使用模式。草药成分最常用于刺激胃饥饿素分泌以增加食物摄入量，并具有潜在的抗肿瘤作用。然而，需要进一步的研究来评估任何有益的效果，从而为使用中药开发新的治疗策略找到线索。2014爱思唯尔爱尔兰有限公司版权所有。
Ethno-pharmacological relevance: Traditional Chinese medicine (TCM) is commonly provided to cancer patients, however, the patterns of prescriptions for this type of medicine in Taiwan are unclear. This study aimed to evaluate the use of traditional Chinese medicine products in colon cancer patients post-surgery in Taiwan and to research patterns of TCM.Material and Methods: This was a cross-sectional study of newly diagnosed colon cancer patients who received surgery between 2004 and 2008 identified from the National Health Insurance Research Database of Taiwan. The prescription patterns and reasons for the use of TCM for colon cancer were analyzed.Results: The results showed that "symptoms, signs and ill-defined conditions" (23.3%) and diseases of the digestive system (16.9%) were the most common reasons for using Chinese herbal medicine. Xiang-shaliu-jun-zi-tang (7.1%), Bu-zhong-yi-qi-tang (4.3%), Jia-wei-xiao-yao-san (4.1%), Shen-Ling-Bai-Zhu-San (3.7%), Ban-Xia-Xie-Xin-Tang (3.4%), Gui-pi-tang (2.4%), Ping-Wei-San (2.4%), Gan-Lu-Yin (2.0%), Bao-He-Wan (1.9%), and Zhen-Ren-Huo-Ming-Yin (1.8%) were the most commonly prescribed single Chinese herbal formulae (CHF) for colon cancer patients post-surgery. Hedyotis diffusa Willd (Bai Hua She She Cao) (5.1%) and Scutellaria barbata (Ban Zhi Lian)(4.8%) were the most commonly prescribed single Chinese herbs.Conclusions: This study identified patterns of TCM use in colon cancer patients post-surgery in Taiwan. The herbal ingredients were most commonly used for stimulate ghrelin secretion to increase food intake and had potential anti-tumor effect. However, further research is required to evaluate any beneficial effects which could identify leads for the development of new treatment strategies using TCM. (C) 2014 Elsevier Ireland Ltd. All rights reserved.