Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis.
Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis.
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DOI:
10.1038/nchembio.159
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发表时间:
2009-06
影响因子:
14.8
通讯作者:
Clardy, Jon
中科院分区:
文献类型:
--
作者:
Oh, Dong-Chan;Poulsen, Michael;Currie, Cameron R.;Clardy, Jon
Fungus-growing ants engage in mutualistic associations with both the fungus they cultivate for food and actinobacteria (Pseudonocardia spp.) that produce selective antibiotics to defend that fungus from specialized fungal parasites. In the first system to be analyzed at the molecular level, the bacterium associated with the ant Apterostigma dentigerum produces dentigerumycin, a cyclic depsipeptide with highly modified amino acids, to selectively inhibit the parasitic fungus (Escovopsis sp.).
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