Exercise capacity and body mass as predictors of mortality among male veterans with type 2 diabetes
Exercise capacity and body mass as predictors of mortality among male veterans with type 2 diabetes
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DOI：
10.2337/dc06-2397
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发表时间：
2007-06-01
期刊：
影响因子：
16.2
通讯作者：
Froelicher, Victor F.
中科院分区：
文献类型：
--
作者：
McAuley, Paul A.;Myers, Jonathan N.;Froelicher, Victor F.
目的 - 证明运动能力和 BMI 与患有 2 型糖尿病的退伍军人群体的死亡率之间的关系。 研究设计和方法 - 排除两名体重不足的患者 (BMI = 30 kg/m(2)) 和运动能力 (= 5.0 最大 MET)。通过 Cox 比例风险评估运动能力、BMI、其他临床变量和全因死亡率之间的关联。研究参与者的死亡率随访至2006 年6 月30 日。结果——在平均4.8 +/- 3.0 年的随访期间，112 名患者死亡，年平均死亡率为2.2%。运动能力每增加 1-MET，就会带来 10% 的生存获益（风险比 0.90 [95% CI 0.82-0.98]；P = 0.01），但 BMI 与死亡率没有显着相关。在调整年龄、种族、检查年份、BMI、是否存在心血管疾病 (CVD) 以及 CVD 危险因素后，糖尿病患者实现了
OBJECTIVE - To demonstrate the relation of exercise capacity and BMI to mortality in a population of mate veterans with type 2 diabetes.RESEARCH DESIGN AND METHODS - After excluding two under-weight patients (BMI = 30 kg/m(2)) and by exercise capacity (= 5.0 maximal METs). The association among exercise capacity, BMI, other clinical variables, and all-cause mortality was assessed by Cox proportiovial hazards. Study participants were followed for mortality up to 30 June 2006.RESULTS - During a mean follow-up of 4.8 +/- 3.0 years, 112 patients died, for an average annual mortality rate of 2.2%. Each 1-MET increase in exercise capacity conferred a 10% survival benefit (hazard ratio 0.90 [95% CI 0.82-0.98]; P = 0.01), but BMI was not significantly associated with mortality. After adjustment for age, ethnicity, examination year, BMI, presence of cardiovascular disease (CVD), and CVD risk factors, diabetic patients achieving