NERVE IMPULSE PROPAGATION ALONG CENTRAL AND PERIPHERAL FAST CONDUCTING MOTOR AND SENSORY PATHWAYS IN MAN
NERVE IMPULSE PROPAGATION ALONG CENTRAL AND PERIPHERAL FAST CONDUCTING MOTOR AND SENSORY PATHWAYS IN MAN
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DOI：
10.1016/0013-4694(85)90006-9
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发表时间：
1985-01-01
期刊：
影响因子：
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通讯作者：
STANZIONE, P
中科院分区：
文献类型：
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作者：
ROSSINI, PM;DISTEFANO, E;STANZIONE, P
对11名健康志愿者的44条肢体进行了检查。记录正中神经和腓神经刺激的脊髓和头皮体感诱发电位，并计算外周（腕-Erb，Erb-颈椎，膝-胸椎）和中枢（颈-头皮，胸-颈椎，脊柱-头皮）传导时间和速度（CT，CV）。刺激正中神经和腓神经的感觉干和混合干，测量其运动和感觉CV。通过皮肤矩形板电极提供高压（880-1870 V）短暂阳极脉冲来进行头皮（手部和腿部肌肉的运动区域）和脊髓刺激（颈部和下胸部水平）的运动反应。测量颅内（头皮-颈椎）和椎管内（颈椎-胸椎）运动通路的CT和CV。还通过F波方法计算了肘颈和膝胸脊柱运动纤维的CT，其值几乎与通过直接脊柱刺激获得的值重叠。在周围神经中远端区，感觉神经的传播速度比运动神经快，而这种差异在更近端的节段（包括神经根）中减少或逆转。在减去突触延迟后，运动神经的头皮-颈部CT略短于感觉神经（6.12 ms vs. 6.18 ms）。头皮-下胸椎以及椎管内感觉通路的CV比运动通路快7-12%（前者为45.3 vs 38.7 m/s;后者为62.65 vs 55.4 m/s）。用这种方法沿全身的沿着中枢和外周神经结构评价快速传导运动和感觉通路。还包括用低电压脉冲头皮刺激脑运动区的初步研究结果。
Limbs (44) from 11 healthy volunteers were examined. Spinal and scalp somatosensory evoked potentials to median and peroneal nerve stimulation were recorded and the peripheral (wrist-Erb, Erb-cervical, knee-thoracic spine) and central (cervical-scalp, thoracic-cervical spine, spine-scalp) conduction times and velocities (CT, CV) were calculated. Sensory and mixed trunks of median and peroneal nerves were also stimulated and their motor and sensory CV in mid-distal districts were measured. Motor reponses to scalp (motor areas for hand and leg muscles) and spinal cord stimulation (cervical and lower thoracic levels) were carried out through skin rectangular plate electrodes delivering high voltage (880-1870 V) brief anodal pulses. The intracranial (scalp-cervical) and intraspinal (cervical-thoracic spine) CT and CV of motor pathways were measured. The elbow-cervical and knee-thoracic spines CT of motor fibers were also calculated through the F wave method, which gave values almost superimposable on those obtained through direct spine stimulation. Nerve propagation was faster in sensory than in motor fibers in peripheral nerver mid-distal districts, while this difference was reduced or reversed in more proximal segments, including nerve roots. The scalp-cervical CT was slightly shorter in motor than in sensory fibers after subtraction of synaptic delays (6.12 vs. 6.18 ms). The scalp-lower thoracic spine, as well as the intraspinal, CV were 7-12% faster in sensory than in motor pathways (45.3 vs. 38.7 m/s for the former; 62.65 vs 55.4 m/s for the latter). Fast conducting motor and sensory pathways were evaluated along central and peripheral nerve structures of the entire body with this method. Preliminary findings on scalp stimulation of brain motor areas with low voltage pulses are also included.