Synthesis of biotinylated OSW-1.

Synthesis of biotinylated OSW-1.
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生物素化 OSW-1 的合成。

DOI:
10.1016/j.bmcl.2009.07.062
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发表时间:
2009
影响因子:
2.7
通讯作者:
Jin,Zhendong
Jin,Zhendong
中科院分区:
医学4区
文献类型:
--
作者:
Kang,Ying;Lou,Changgang;Ahmed,KausarBegamRiaz;Huang,Peng;Jin,Zhendong

文献摘要

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OSW-1是一种高效的抗癌天然皂苷,其作用方式未知。为了确定其细胞靶标,在九个步骤中成功合成了生物素化的OSW-1。
OSW-1 is a highly potent anticancer natural saponin with an unknown mode of action. To determine its cellular target(s) biotinylated OSW-1 was successfully synthesized in nine steps.