Passive cavitation imaging with ultrasound arrays
Passive cavitation imaging with ultrasound arrays
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DOI：
10.1121/1.3238260
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发表时间：
2009-12-01
影响因子：
2.4
通讯作者：
Mast, T. Douglas
中科院分区：
文献类型：
--
作者：
Salgaonkar, Vasant A.;Datta, Saurabh;Mast, T. Douglas
提出了一种利用超声阵列对空化声发射进行被动成像的方法，该方法在超声消融实时监测中具有潜在的应用前景。为了创建这样的图像，微泡发射被成像阵列被动感知，并在多个深度动态聚焦。本文通过求解菲涅耳近似下的瑞利-索默菲尔德积分，得到了被动像的解析表达式，并对被动像进行了仿真。一个192个单元的阵列被用来产生被动图像，实时的，从520千赫的超声波被1毫米钢丝散射。从被动图像中准确估计目标的方位位置。然后，在520 kHz的盐水溶液中被动成像稳定和惯性空化。在生理盐水样本中形成的气泡簇在被动图像和b扫描上都一致。利用牛肝脏的宽带辐射在2.2兆赫兹进行超声处理，也产生了被动图像。在图像和源光束形状之间发现了一致，表明有能力在原位绘制治疗超声光束。讨论了这些宽带发射、声振幅和暴露条件之间的关系。
A method is presented for passive imaging of cavitational acoustic emissions using an ultrasound array, with potential application in real-time monitoring of ultrasound ablation. To create such images, microbubble emissions were passively sensed by an imaging array and dynamically focused at multiple depths. In this paper, an analytic expression for a passive image is obtained by solving the Rayleigh-Sommerfield integral, under the Fresnel approximation, and passive images were simulated. A 192-element array was used to create passive images, in real time, from 520-kHz ultrasound scattered by a 1-mm steel wire. Azimuthal positions of this target were accurately estimated from the passive images. Next, stable and inertial cavitation was passively imaged in saline solution sonicated at 520 kHz. Bubble clusters formed in the saline samples were consistently located on both passive images and B-scans. Passive images were also created using broadband emissions from bovine liver sonicated at 2.2 MHz. Agreement was found between the images and source beam shape, indicating an ability to map therapeutic ultrasound beams in situ. The relation between these broadband emissions, sonication amplitude, and exposure conditions are discussed.