Comparison of Human Milk Fatty Acid Composition of Women From Cambodia and Australia
Comparison of Human Milk Fatty Acid Composition of Women From Cambodia and Australia
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DOI：
10.1177/0890334418772279
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发表时间：
2018-08-01
影响因子：
2.6
通讯作者：
Zhou, Shao J.
中科院分区：
文献类型：
--
作者：
Gao, Chang;Liu, Ge;Zhou, Shao J.
背景：母乳是 omega-3 长链多不饱和脂肪酸的丰富来源，人们认为这种脂肪酸对大脑发育很重要。与西方妇女的数据相比，缺乏有关柬埔寨妇女母乳脂肪酸组成的数据。 研究目的：本研究的目的是确定居住在柬埔寨的妇女的母乳脂肪酸组成，并将其与居住在澳大利亚的妇女进行比较。方法：从产后 3 至 4 个月收集柬埔寨（n = 67）和澳大利亚（n = 200）母亲的母乳样本。使用毛细管气相色谱法分析脂肪酸成分，然后用氯仿/甲醇 (2:1 v/v) 进行 Folch 提取，并通过重量分析法测量脂肪含量。结果：与澳大利亚参与者相比，柬埔寨参与者的母乳中总脂肪含量显着较低（2.90 vs. 3.45 g/dL，p = .028），亚油酸百分比较低（9.30% vs. 10.66%，p < .0001）和 α-亚麻酸（0.42% vs. 0.95%，p < .0001），但花生四烯酸（0.68% vs. 0.38%，p < .0001）和二十二碳六烯酸（0.40% vs. 0.23%，p < .0001）的百分比较高。结论：母乳脂肪酸组成存在差异柬埔寨和澳大利亚参与者之间的差异可能是由于两个人群之间饮食模式的差异造成的。
Background: Human milk is a rich source of omega-3 long-chain polyunsaturated fatty acids, which are postulated to be important for brain development. There is a lack of data on the human milk fatty acid composition of Cambodian women compared with data from Western women.Research Aim: The aim of this study was to determine the human milk fatty acid composition of women living in Cambodia and compare it with that of women living in Australia.Method: Human milk samples from Cambodian (n = 67) and Australian (n = 200) mothers were collected at 3 to 4 months postpartum. Fatty acid composition was analyzed using capillary gas chromatography followed by Folch extraction with chloroform/methanol (2: 1 v/v), and fat content was measured gravimetrically.Result: Compared with Australian participants, human milk from Cambodian participants contained a significantly lower level of total fat (2.90 vs. 3.45 g/dL, p = .028), lower percentages of linoleic acid (9.30% vs. 10.66%, p < .0001) and a-linolenic acid (0.42% vs. 0.95%, p < .0001), but higher percentages of arachidonic acid (0.68% vs. 0.38%, p < .0001) and docosahexaenoic acid (0.40% vs. 0.23%, p < .0001).Conclusion: Differences in human milk fatty acid composition between Cambodian and Australian participants may be explained by differences in the dietary patterns between the two populations.