GENETICS OF DACUS-OLEAE .5. CHANGES OF ESTERASE POLYMORPHISM IN A NATURAL POPULATION FOLLOWING INSECTICIDE CONTROL-SELECTION OR DRIFT
GENETICS OF DACUS-OLEAE .5. CHANGES OF ESTERASE POLYMORPHISM IN A NATURAL POPULATION FOLLOWING INSECTICIDE CONTROL-SELECTION OR DRIFT
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DOI：
10.1111/j.1558-5646.1971.tb01904.x
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发表时间：
1971-01-01
期刊：
影响因子：
3.3
通讯作者：
TSAKAS, S
中科院分区：
文献类型：
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作者：
KRIMBAS, CB;TSAKAS, S
在实验室实验中，已发现有机磷杀虫剂乐果作为一种选择剂对基因A酯酶多态性的成年Dacus oleae，选择对沉默的等位基因。然而，在小的自然人口的Haghioi Apostoli乐果似乎并没有初步远景作为一种选择剂，相反，观察到的基因频率的变化是人口规模减少（遗传漂变）的结果。得出这一结论的方法被认为是区分自然群体中基因频率变化的选择和漂移的一般方法。还给出了酶多态性突变率的间接估计值（10- 3至10-4）。然而，这一估计包括了作为模拟突变因素的迁移。
In laboratory experiments it has been found that the organophosphate insecticide dimethoate acts as a selective agent on gene A esterase polymorphism of adult Dacus oleae, selecting against the silent isoallele. However, in the small natural population of Haghioi Apostoli dimethoate does not seem prima vista to act as a selective agent; instead, observed gene frequency changes are a consequence of population size reduction (genetic drift). The method used to arrive at this conclusion is proposed as a general method for distinguishing selection from drift as a cause of gene frequency changes in natural populations. An indirect estimate of mutation rate for enzyme polymorphisms is also given (10-3to 10-4). This estimate, however, includes migration as a factor mimicking mutation.