Healthy eating, aerobic and resistance training in youth (HEARTY): Study rationale, design and methods
Healthy eating, aerobic and resistance training in youth (HEARTY): Study rationale, design and methods
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DOI：
10.1016/j.cct.2012.04.004
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发表时间：
2012-07-01
影响因子：
2.2
通讯作者：
Sigal, R. J.
中科院分区：
文献类型：
--
作者：
Alberga, A. S.;Goldfield, G. S.;Sigal, R. J.
目的：青年健康饮食有氧和阻力训练（HEARTY）试验（ClinicalTrials.Gov #NC 100195858）的目的是检查阻力训练（有和没有有氧训练）对14-18岁久坐、青春期后超重或肥胖青少年体脂百分比的影响。本文介绍了HEARTY研究的基本原理、设计和方法。方法：经过4周的监督低强度运动磨合期后，将304名体重指数>=年龄和性别第85百分位数的超重或肥胖青少年随机分为4组22周（5个月）：饮食+有氧运动，饮食+阻力运动，饮食+有氧运动和阻力运动相结合，或饮食只等待列表控制。所有参与者都接受了旨在促进健康饮食的饮食咨询，每日最大能量不足为-250 kcal。结果：主要结果是通过磁共振成像测量的体脂百分比。次要结果包括人体测量学的变化，区域身体成分，静息能量消耗，心肺功能，肌肉骨骼健康，心脏代谢风险标志物，和心理health.Summary：据我们所知，HEARTY是最大的临床试验研究的影响有氧训练，阻力训练，有氧和阻力相结合的训练对超重和肥胖青少年的肥胖和心脏代谢风险标志物的变化。研究结果将具有重要的临床意义的作用，阻力训练应发挥在青少年肥胖及其共病的管理。(C)2012 Elsevier Inc. All rights reserved.
Purpose: The objective of the Healthy Eating Aerobic and Resistance Training in Youth (HEARTY) trial (ClinicalTrials.Gov # NC100195858) was to examine the effects of resistance training, with and without aerobic training, on percent body fat in sedentary, post-pubertal overweight or obese adolescents aged 14-18 years. This paper describes the HEARTY study rationale, design and methods.Methods: After a 4-week supervised low-intensity exercise run-in period, 304 overweight or obese adolescents with a body mass index >= 85th percentile for age and sex were randomized to 4 groups for 22 weeks (5 months): diet + aerobic exercise, diet + resistance exercise, diet + combined aerobic and resistance exercise, or a diet only waiting-list control. All participants received dietary counseling designed to promote healthy eating with a maximum daily energy deficit of -250 kcal.Outcomes: The primary outcome is percent body fat measured by Magnetic Resonance Imaging. Secondary outcomes include changes in anthropometry, regional body composition, resting energy expenditure, cardiorespiratory fitness, musculoskeletal fitness, cardiometabolic risk markers, and psychological health.Summary: To our knowledge, HEARTY is the largest clinical trial examining effects of aerobic training, resistance training, and combined aerobic and resistance training on changes in adiposity and cardiometabolic risk markers in overweight and obese adolescents. The findings will have important clinical implications regarding the role that resistance training should play in the management of adolescent obesity and its co-morbidities. (C) 2012 Elsevier Inc. All rights reserved.