Relation of the New Respiratory Agents to Acute Respiratory Diseases
Relation of the New Respiratory Agents to Acute Respiratory Diseases
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DOI：
10.2105/ajph.45.7.915
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发表时间：
1955-07-01
期刊：
影响因子：
--
通讯作者：
Dingle, John H.
中科院分区：
文献类型：
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作者：
Ginsberg, Harold S.;Gold, Eli;Dingle, John H.
Hilleman 和 Werner 分离出的 RI-67 病原体与急性呼吸道疾病 (ARD) 明显相关。然而，有证据表明，免疫学上不同的其他因素也导致了这种综合征的发生。获得的数据表明，偶有 ARD 病例有肺部浸润。 1954 年 7 月和 8 月期间，从克利夫兰的一个家庭研究人群中发生的非细菌性咽炎病例中，分离出了腺样变性 (AD) 病原体。尽管至少有一种其他免疫学类型被证明与临床病例相关，但 III 型病毒是所涉及的主要病毒。获得的数据清楚地表明，分离出的病毒是非细菌性咽炎病例的病原体。
The RI-67 agent isolated by Hilleman and Werner was clearly related to the acute respiratory disease (ARD). Evidence indicates, however, that other agents which are immunologically distinct also are responsible for cases of this syndrome. The data obtained imply that occasional cases of ARD have pulmonary infiltration. From cases of nonbacterial pharyngitis which occurred in Cleveland in a family-study population during July and August, 1954, adenoid degeneration (AD) agents were isolated. The Type III agent was the predominant virus implicated, although at least one other immunologic type was shown to be associated with clinical cases. The data obtained clearly imply that the viruses isolated were the causal agents of the cases of non-bacterial pharyngitis.