Prevalence of metabolic syndrome at age 16 using the International Diabetes Federation paediatric definition
Prevalence of metabolic syndrome at age 16 using the International Diabetes Federation paediatric definition
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DOI：
10.1136/adc.2007.132951
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发表时间：
2008-11-01
影响因子：
5.2
通讯作者：
Vaarasmaki, M.
中科院分区：
文献类型：
--
作者：
Pirkola, J.;Tammelin, T.;Vaarasmaki, M.
目的：我们使用新的国际糖尿病联合会（IDF）儿科定义估计青少年代谢综合征（MS）的患病率，并将其与使用IDF成人定义和其他五个先前发表的定义估计的患病率进行比较。设计：基于北方芬兰出生队列的前瞻性一般人群的横断面调查，1986年（NFBC 1986），年龄16岁。设置：芬兰出生队列。参与者：5665名青少年（男2862例，女2803例）。主要观察指标：采用不同定义的MS患病率。使用IDF儿科定义，16岁时MS的总体患病率为2.4%（95% CI 2.0 - 2.8%）。使用IDF成人定义的总体患病率较低，1.7%（CI 1.3至2.0%，欧洲腰围截断值）和1.0%（CI 0.7至1.3%，北美截断值）。结论：在16岁的青少年，儿科IDF定义呈现出较高的患病率估计比成人定义。
Objective: We estimated the prevalence of metabolic syndrome (MS) in adolescents, using the new International Diabetes Federation (IDF) paediatric definition and compared this with prevalence estimated using the IDF adult definition and five other previously published definitions.Design: Cross-sectional survey in the prospective general population-based Northern Finland Birth Cohort 1986 (NFBC 1986) at age 16 years.Setting: Birth cohort in Finland.Participants: 5665 adolescents (2862 males and 2803 females) clinically examined in 2001-2002.Main outcome measures: The prevalence of MS using different definitions.Results: The overall prevalence of MS using the IDF paediatric definition was 2.4% (95% CI 2.0 to 2.8%) at the age of 16 years. Using the IDF adult definition the overall prevalence was lower, 1.7% (CI 1.3 to 2.0%, European cut-offs for waist circumference) and 1.0% (CI 0.7 to 1.3%, North American cut-offs).Conclusion: In 16-year-old adolescents, the paediatric IDF definition rendered a higher prevalence estimate than the adult definition.