B cells latently infected with murine gammaherpesvirus 68 (MHV‐68) are present in the mouse thymus–A step toward immune evasion?
B cells latently infected with murine gammaherpesvirus 68 (MHV‐68) are present in the mouse thymus–A step toward immune evasion?
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小鼠胸腺中存在潜伏感染鼠伽马疱疹病毒 68 (MHVâ68) 的 B 细胞——这是免疫逃避的一步吗？
DOI：
10.1002/eji.201847886
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发表时间：
2018
影响因子：
5.4
通讯作者：
Adler H.
中科院分区：
文献类型：
--
作者：
Yamano T;Steinert M;Steer B;Klein L;Hammerschmidt W;Adler H.
我们发现在胸腺中存在潜伏感染伽马疱疹病毒的B细胞。这可能导致T细胞对某些病毒表位的功能性耐受。可以想象的是，来自其他病毒或病原体的抗原也可能被传递到胸腺，以逃避免疫。
We show that latently gammaherpesvirus‐infected B cells are present in the thymus. This could result in a functional T‐cell tolerance against certain viral epitopes. It is conceivable that also antigens from other viruses or pathogens may be conveyed to the thymus for their immune evasion.
影响因子：
6.7
作者：
Sattler C;Steer B;Adler H
通讯作者：
Adler H