Time Trade-Off Value Set for EQ-5D-3L Based on a Nationally Representative Chinese Population Survey

Time Trade-Off Value Set for EQ-5D-3L Based on a Nationally Representative Chinese Population Survey
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DOI:
10.1016/j.jval.2018.04.1370
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发表时间:
2018-11-01
期刊:
影响因子:
4.5
通讯作者:
Chen, Jiaying
Chen, Jiaying
中科院分区:
医学2区
文献类型:
--
作者:
Zhuo, Lang;Xu, Ling;Chen, Jiaying

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目的:采用时间权衡法(TTO)获得具有全国代表性的中国人EuroQol三维五维量表值集。方法:采用多阶段、分层、整群随机抽样的方法。研究设计遵循了英国健康测量和评估方案。每个受访者价值11个随机状态加上状态33333和“无意识”使用TTO方法在面对面的采访。三种类型的模型进行了探讨:普通最小二乘,一般最小二乘,加权最小二乘模型。结果:共对5939名15岁及以上的居民进行了采访。其中,5503满意的受访者被纳入构建模型。一个普通的最小二乘模型,包括10个假人没有常数和N3的平均绝对误差为0.083和预测值和平均值之间的相关系数为0.899。两个模型的拟合优度指标基本一致。结论:与在城市地区进行的研究相比,我们的研究中的TTO值更高,这反映了农村地区的较高值。除了估值程序之外,其他几个方面可能也影响了结果,例如人口因素以外的因素,如对生死的看法和相信来世,这些都需要进一步调查。未来使用三水平EuroQol五维问卷的研究应考虑使用基于中国人群全国代表性样本的该值集。
Objectives: To obtain a nationally representative Chinese three-level EuroQol five-dimensional questionnaire value set based on the time trade-off (TTO) method. Methods: A multistage, stratified, clustered random nationally representative Chinese sample was used. The study design followed an adapted UK Measurement and Valuation of Health protocol. Each respondent valued 11 random states plus state 33333 and "unconscious" using the TTO method in face-to-face interviews. Three types of models were explored: ordinary least squares, general least squares, and weighted least squares models. Results: In total, 5939 inhabitants aged 15 years and older were interviewed. Of these, 5503 satisfactorily interviewed participants were included in constructing models. An ordinary least squares model including 10 dummies without constant and N3 had a mean absolute error of 0.083 and a correlation coefficient of 0.899 between the predicted and mean values. Goodness-of-fit indices of two models based on split subsample were similar. Conclusions: TTO values were higher in our study compared with those in a study carried out in urban areas, which is mirrored by the higher values in rural areas. Several other aspects, in addition to the valuation procedure, might have influenced the results, such as factors beyond demographic factors such as view on life and death and believing in an afterlife, which need further investigation. Future studies using the three-level EuroQol five-dimensional questionnaire should consider using this value set based on a nationally representative sample of the Chinese population.