Sexual Function in Adolescent and Young Adult Survivors of Lower Extremity Bone Tumors

Sexual Function in Adolescent and Young Adult Survivors of Lower Extremity Bone Tumors
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DOI:
10.1002/pbc.22761
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发表时间:
2010-12-15
影响因子:
3.2
通讯作者:
Greenberg, Mark
Greenberg, Mark
中科院分区:
医学3区
文献类型:
--
作者:
Barrera, Maru;Teall, Tanya;Greenberg, Mark

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本研究调查了青春期和青壮年骨肿瘤幸存者的性功能、与手术治疗的性别差异、抑郁症状、总体自我价值感和身体残疾程序的关系。28名参与者(年龄范围18-32岁)完成了性别相关的性功能测量、抑郁症状、总体自我价值和身体残疾分析,手术干预被分组为四肢弹簧手术(LS,结果男性存活者的尾部性功能评分(P=0.0 5 0)、性冲动(P=0.0 0 2)、性幻想或性梦频度(P=0.0 2 1)显著高于女性(P=0.0 2 1),身体功能评分也明显好于女性(P=0.0 12),LS的性幻想和性梦频度显著低于AMP(P=0.0 48),性经历频度(P=0.0 16)显著低于AMP(P=0.0 0 4)和低于AMP的自我价值感(P=0.037)。结论这些结果表明,与Van nes旋转成形术和截肢幸存者相比,接受保肢手术的男性幸存者的性功能更好,性功能抑郁症状和自我感觉更差。
Background Improving survival rates and new surgical options have led to increased interest regarding late effects and quality of life in adolescent and young adult survivors of bone cancers including their sexual functioning This study investigated sexual functioning in adolescent and young adult survivors of lower limb bone tumors, in relation to surgical treatments gender differences depressive symptoms, global self worth and physical disability Procedure Twenty eight participants (age range 18-32 years) completed measures of gender specific sexual function depressive symptoms global self worth and physical disability For analysis, surgical intervention was grouped into limb spring surgeries (LS, allograft fusion and endoprosthesis) and amputation or Van Nes rotationplasty (AMP) Results Male survivors reported significantly higher scores than females on tail sexual function scores (P = 0 050) sexual drive (P = 0 002) and frequency of sexual thoughts fantasies or erotic dreams (P = 0 021) Men also reported significantly better physical functioning scores than women (P = 0 012) LS scored significantly lower on frequency of sexual thoughts fantasies and erotic dreams (P = 0 048) and frequency of sexual experiences (P = 0 016) compared with AMP In addition LS reported significantly more depressive symptoms scores (P = 0 004) and lower self worth scores (P = 0 037) than AMP Conclusions These results suggest that male survivors of lower extremity bone tumors experience better sexual functioning than women Survivors of limb sparing surgeries struggle with sexual function depressive symptoms and poor self perception compared to Van Nes rotationplasty and amputation survivors Pediatr Blood Cancer 2010 55 1370-1376 (C) 2010 Wiley Liss Inc