Initial presentation of systemic lupus erythematosus masquerading as bacterial meningitis.
Initial presentation of systemic lupus erythematosus masquerading as bacterial meningitis.
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发表时间：
2001-11
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通讯作者：
Juan Dong;S. Suwanvecho;Lugen Chen;Yi-Kong Keung
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作者：
Juan Dong;S. Suwanvecho;Lugen Chen;Yi-Kong Keung
系统性红斑狼疮（SLE）的神经精神表现是有据可查的，最近进行了审查。多达14%至75%的SLE患者最终会出现不同程度的神经精神症状。然而，SLE患者最初出现此类表现相对罕见。根据对140例SLE患者的回顾性研究，只有5例（3%）患者最初有神经精神症状，只有1例患者最初有无菌性脑膜炎。通过检索MEDLINE，我们只能找到10例SLE相关的无菌性脑膜炎从1966年至2000年。我们描述了一例SLE相关的无菌性脑膜炎，伴有发热、头痛、颈部强直和化脓性脑膜炎的典型实验室检查结果。
Neuropsychiatric manifestations of systemic lupus erythematosus (SLE) are well documented and recently reviewed. As many as 14% to 75% of patients with SLE eventually develop various degrees of neuropsychiatric manifestations. It is relatively rare, however, for patients with SLE to have such manifestations initially. According to a retrospective study of 140 patients with SLE, only 5 patients (3%) initially had neuropsychiatric manifestations, and only 1 patient initially had aseptic meningitis. Searching through MEDLINE, we were able to find only 10 cases of SLE-related aseptic meningitis from 1966 to 2000. We describe a case of SLE-related aseptic meningitis with fever, headache, neck rigidity, and laboratory findings otherwise typical of pyogenic meningitis.