Quantitative methods in research on complementary and alternative medicine - A methodological manifesto
Quantitative methods in research on complementary and alternative medicine - A methodological manifesto
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DOI：
10.1097/00005650-199711000-00001
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发表时间：
1997-11-01
期刊：
影响因子：
3
通讯作者：
Jonas, WB
中科院分区：
文献类型：
--
作者：
Levin, JS;Glass, TA;Jonas, WB
目标。本文总结了美国国立卫生研究院(NIH)为支持NIH替代医学办公室而召集的定量方法工作组的审议情况。该工作组负责确定可应用于补充和替代医学实证研究的研究设计和数据分析方法。这一指控是广泛和包容的，涉及替代疗法的评估、补充医疗系统基础科学的调查、健康促进和疾病预防的研究以及卫生服务研究。结果：工作组制定了一份“方法学宣言”，总结了7项推荐的替代医学研究方法学指南。这些建议强调了现有研究方法和分析程序的稳健性，尽管替代医学存在实质性的非常规。结论与许多研究人员和替代医学从业者的断言相反，已建立的方法(如实验试验、观察流行病学、社会调查研究)和数据分析程序(如方差分析、Logistic回归、多变量建模技术)在解决与替代医学有关的大多数研究问题方面相当令人满意，从治疗疗效的临床研究到发病机制和康复机制的基础科学研究。
OBJECTIVES. This article summarizes the deliberations of the Quantitative Methods Working Group convened by the National Institutes of Health (NIH) in support of the NIH Office of Alternative Medicine.METHODS. The working group was charged with identifying methods of study design and data analysis that can be applied to empirical research on complementary and alternative medicine. This charge was broad and inclusive and addressed the evaluation of alternative therapies, the investigation of the basic science of complementary medical systems, studies of health promotion and disease prevention, and health services research.RESULTS. The working group produced a ''methodological manifesto,'' a summary list of seven recommended methodological guidelines for research on alternative medicine. These recommendations emphasize the robustness of existing research methods and analytic procedures despite the substantive unconventionality of alternative medicine.CONCLUSIONS. Contrary to the assertions of many researchers and alternative practitioners, established methodologies (eg, experimental trials, observational epidemiology, social survey research) and data-analytic procedures (eg, analysis of variance, logistic regression, multivariate modeling techniques) are quite satisfactory for addressing the majority of study questions related to alternative medicine, from clinical research on therapeutic efficacy to basic science research on mechanisms of pathogenesis and recovery.