The patient-oriented eczema measure - Development and initial validation of a new tool for measuring atopic eczema severity from the patients' perspective
The patient-oriented eczema measure - Development and initial validation of a new tool for measuring atopic eczema severity from the patients' perspective
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DOI：
10.1001/archderm.140.12.1513
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发表时间：
2004-12-01
影响因子：
--
通讯作者：
Williams, HC
中科院分区：
文献类型：
--
作者：
Charman, CR;Venn, AJ;Williams, HC
目的：为了开发一个简单的，有效的，可重复的，易于理解的病人为导向的评估措施，监测疾病活动的儿童和成人与特应性eczema.Design：定性半结构化的病人访谈确定了特应性湿疹的症状列表。在更大的患者群体中对这些症状进行定量分析，以确定哪些症状对患者是重要的，并作为评分系统的一部分进行监测。设置：英国诺丁汉大学医院女王医学中心皮肤科门诊部和5个当地综合诊所。患者：435例特应性湿疹患者。结果：使用前一周发生频率的简单5点量表将7种症状纳入最终的患者导向湿疹测量中，最大总分为28。针对皮肤病生活质量指数、儿童皮肤病生活质量指数和患者总体严重程度评估的有效性测试显示出良好的相关性（分别为r=0.78、r=0.73和r=0.81; P
Objective: To develop a simple, valid, repeatable, and readily understandable patient-oriented assessment measure for monitoring disease activity in children and adults with atopic eczema.Design: Qualitative semistructured patient interviews identified a list of symptoms of atopic eczema. These symptoms were quantitatively analyzed in a larger patient population to identify which symptoms were important to patients and amenable to monitoring as part of a scoring system.Setting: The outpatient Department of Dermatology at the Queen's Medical Centre, University Hospital, Nottingham, England, and 5 local general practices.Patients: Four hundred thirty-five patients with atopic eczema.Results: Seven symptoms were incorporated into the final patient-oriented eczema measure using a simple 5-point scale of frequency of occurrence during the previous week, with a Maximum total score of 28. Validity testing against the Dermatology Life Quality Index, Children's Dermatology Life Quality index, and patients' global severity assessments showed good correlation (r=0.78, r=0.73, and r=0.81, respectively; P