Functional link between distal vasodilation and sleep-onset latency?
Functional link between distal vasodilation and sleep-onset latency?
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DOI：
10.1152/ajpregu.2000.278.3.r741
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发表时间：
2000-03-01
影响因子：
2.8
通讯作者：
Wirz-Justice, A
中科院分区：
文献类型：
--
作者：
Kr채uchi, K;Cajochen, C;Wirz-Justice, A
体温调节过程长期以来一直被认为与人类睡眠的启动有关。这项研究的目的是评估热量损失在睡眠启动中的作用，在经过修改以允许夜间睡眠的恒定常规方案的受控条件下。热损失通过远端到近端皮肤温度梯度(DPG)间接测量。逐步回归分析表明，DPG是入睡潜伏期的最佳预测变量(与核心体温或其变化率、心率、褪黑素发作和主观嗜睡评分相比)。这项研究提供的证据表明，远端皮肤区域的选择性血管扩张(因此热量损失)促进了睡眠的快速开始。
Thermoregulatory processes have long been implicated in initiation of human sleep. The purpose of this study was to evaluate the role of heat loss in sleep initiation, under the controlled conditions of a constant-routine protocol modified to permit nocturnal sleep. Heat loss was indirectly measured by means of the distal-to-proximal skin temperature gradient (DPG). A stepwise regression analysis revealed that the DPG was the best predictor variable for sleep-onset latency (compared with core body temperature or its rate of change, heart rate, melatonin onset, and subjective sleepiness ratings). This study provides evidence that selective vasodilation of distal skin regions (and hence heat loss) promotes the rapid onset of sleep.