Multi-angle Oblique Optical Coherence Tomography
Multi-angle Oblique Optical Coherence Tomography
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发表时间：
2008
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通讯作者：
M. Malmström
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作者：
M. Malmström
光学相干层析成像（OCT）是一种非侵入性的高分辨率方法，用于测量1/2/3维散射介质（如皮肤）的反射率。该方法已被广泛应用于多种医学领域和组织光学特性的测量，本文开发的软件能够通过叠加多个不同角度的OCT测量值来显示隐藏在阴影体积中的特征，称为多角度倾斜光学相干断层成像（MAO-OCT）。测量结果在软件中自动和手动对齐。他们还测试了6个不同的高通强度过滤器（HPIF），并使用4种不同的方法来减少尺寸，以加快计算。软件的自动对齐测试了一个倾斜的计算机生成的测试在9个角度和5个不同的阴影强度。MAO-OCT是可能消除OCT中的一些阴影，但它带来了降低清晰度的代价。误差主要取决于样品折射率的差异，软件能够自动校准90%的人工测量值和60%的OCT测量值。阴影强度和调整大小的方法对测量仪的自动对齐没有明显的影响。
Optical Coherence Tomography (OCT) is a non-invasive high-resolutionmethod for measuring the reectance of scattering media in 1/2/3D, e.g.skin. The method has been used in a number of dierent medical elds andfor measurement of tissue optical properties.The software developed in this thesis is able to display features hidden ina shadowed volume by adding multiple OCT measurements taken at obliqueangles, a technique here called Multiple-Angle Oblique Optical CoherenceTomography (MAO-OCT).Three dierent objects with were measured at 5 to 9 angles. The measurementswere automatically and manually aligned in the software. They werealso tested with 6 dierent high pass intensity lters (HPIF) and reduced insize using 4 dierent methods to speed up calculations.The software's automatic alignment was tested with one tilted computergenerated test at 9 angles and with 5 dierent shadow strengths.With MAO-OCT it is possible to remove some eects of shadows in OCT,though it comes with a cost of reduced sharpness. The errors depend muchon the dierences in index of refraction in the sample.The software managed to automatically align 90% of the articial measurements,and 60% of the OCT measurements. The shadow strength andthe resize method had no noticeable eect on the automatic alignment of themeasurements.