In vivo approaches to assessing the toxicity of quantum dots.
In vivo approaches to assessing the toxicity of quantum dots.
复制标题
评估量子点毒性的体内方法。
DOI：
10.1007/978-1-4939-1280-3_14
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kavanagh,TerranceJ
中科院分区：
文献类型：
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作者：
Scoville,DavidK;Schaupp,ChristopherM;Baneyx,François;Kavanagh,TerranceJ
量子点 (QD) 的小尺寸和重金属成分，加上其不断增长的消费产品和生物医学研究应用，引起了人们对其安全性的担忧。在生产 QD 产品的职业环境中，吸入是一种可能的接触途径。由于目前的研究表明量子点可能会引起呼吸道炎症和毒性，因此重要的是可以使用多种方法来进一步表征这种潜在的呼吸道危害。本章主要关注模拟吸入和评估量子点肺毒性的体内方法。
The small size and heavy metal composition of quantum dots (QDs) combined with their growing consumer product and biomedical research applications have generated concern over their safety. In an occupational setting where QD-enabled products are being manufactured, inhalation is a likely route of exposure. Since current research indicates that QDs could cause inflammation and toxicity in the respiratory tract, it is important that a variety of methods be available to further characterize this potential respiratory hazard. This chapter focuses primarily on in vivo methods for modeling the inhalation and assessing the pulmonary toxicity of QDs.