Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions.
Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions.
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DOI：
10.1016/j.ajog.2011.10.878
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发表时间：
2012-02
影响因子：
9.8
通讯作者：
Kuklina EV
中科院分区：
文献类型：
--
作者：
Bateman BT;Bansil P;Hernandez-Diaz S;Mhyre JM;Callaghan WM;Kuklina EV
在以人口为基础的分娩样本中，确定原发性和继发性慢性高血压的患病率、趋势和结局。1995-2008年全国住院病人样本中估计有56,494,634例分娩。使用回归模型评估原发性和继发性慢性高血压与胎儿和母体不良结局的关联，并计算调整后的人群归因分数。在研究期间，原发性和继发性高血压的患病率分别从1995/1996年的0.90%上升到2007/2008年的1.52% （p <0.001）和从0.07%上升到0.24% （p <0.001）。慢性高血压的人群归因比例在许多孕产妇不良结局中都是相当大的，包括急性肾衰竭（21%）、肺水肿（14%）、先兆子痫（11%）和住院死亡率（10%）。原发性和继发性高血压都与不良妊娠结局密切相关，并占孕产妇发病率的很大一部分。需要对这一领域的研究工作进行优先排序。
To define the prevalence, trends, and outcomes of primary and secondary chronic hypertension in a population-based sample of deliveries. An estimated 56,494,634 deliveries were identified from the 1995-2008 Nationwide Inpatient Sample. The association of primary and secondary chronic hypertension with adverse fetal and maternal outcomes was evaluated using regression modeling and adjusted population attributable fractions were calculated. During the study period, the prevalence of primary and secondary hypertension increased from 0.90% in 1995/1996 to 1.52% in 2007/2008 (p for trend <0.001) and from 0.07% to 0.24% (p for trend <0.001), respectively. The population attributable fraction for chronic hypertension was considerable for many maternal adverse outcomes, including acute renal failure (21%), pulmonary edema (14%), preeclampsia (11%), and in-hospital mortality (10%). Primary and secondary hypertension were both strongly associated with adverse pregnancy outcomes and accounted for a substantial fraction of maternal morbidity. Prioritizing research efforts in this area is needed.
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影响因子：
158.5
作者：
Sibai, BM;Lindheimer, M;Dombrowski, M
通讯作者：
Dombrowski, M
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作者：
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