Assessing the COVID-19 diagnostic laboratory capacity in Indonesia in the early phase of the pandemic.
Assessing the COVID-19 diagnostic laboratory capacity in Indonesia in the early phase of the pandemic.
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DOI：
10.4103/2224-3151.294307
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发表时间：
2020-09-01
影响因子：
--
通讯作者：
Wahyuni, Indira Rezky
中科院分区：
文献类型：
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作者：
Hendarwan, Harimat;Syachroni, Syachroni;Wahyuni, Indira Rezky
由于对严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）实验室诊断检测的需求，2019年冠状病毒病（COVID-19）大流行给各国带来了巨大负担。本文报告了我们在大流行应对的早期阶段快速评估印度尼西亚COVID-19实验室检测能力的经验。通过在3月23日至4月2日期间进行的基于问卷的调查，我们估计了44个设施（不包括国家转诊实验室）可完成的每日检测量，这些实验室最初被指定为COVID-19诊断实验室。能力限制是缺乏试剂和设备，人力资源有限；由于这些限制，大多数实验室尚未开始运作。一个主要障碍是依赖进口供应品和相关的采购时间。通过增加实验室数量和优化现有设施，扩大实时聚合酶链反应检测能力显然是主要优先事项。我们还评估了在该国转诊医院使用快速分子检测仪的潜在产量。即使假设这一潜力可以被挖掘出来，在病例激增的情况下，一些省份的诊断服务仍然很差。自这次快速评估以来，指定的COVID-19实验室数量有所增加，到2020年7月1日为163个。2020年7月29日，一天内检测的标本数量首次超过3万个，实现了世卫组织每周每1000名居民检测1例的能力目标。
The coronavirus disease 2019 (COVID-19) pandemic has put a great burden on countries as a result of the demand for laboratory diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This paper reports our experiences in rapidly assessing Indonesia's COVID-19 laboratory testing capacity in the early phase of the pandemic response. Through a questionnaire-based survey carried out between 23 March and 2 April, we estimated the daily tests that could be done by the 44 facilities, excluding the national referral laboratory, first assigned to be COVID-19 diagnostic laboratories. The capacity constraints were lack of reagents and equipment, and limited human resources; because of these constraints, most of the laboratories were not yet operational. A major hindrance was reliance on imported supplies and the associated procurement time. Expanding real-time polymerase chain reaction testing capacity, through increased numbers of laboratories and optimization of existing facilities, was clearly the main priority. We also assessed the potential yield from using rapid molecular testing machines in the country's referral hospitals. Even assuming this potential could be tapped, several provinces would still be poorly served by diagnostic services in the event of a surge in cases. Since this rapid assessment, the number of designated COVID-19 laboratories has increased and, by 1 July 2020, was 163. On 29 July 2020, for the first time, the number of specimens examined in a day reached more than 30 000, achieving the WHO testing capacity target of 1 in 1000 inhabitants per week.