Proteoforms and Proteoform Families: Past, Present, and Future.
Proteoforms and Proteoform Families: Past, Present, and Future.
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DOI：
10.1007/978-1-0716-2325-1_1
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发表时间：
2022
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人类蛋白质组项目是一项雄心勃勃的国际努力，旨在加速蛋白质组分析技术的发展，并为人类和模式生物建立全面的蛋白质组图谱。蛋白形式是生物学中功能的最终分子效应物，因此是理解该功能的核心。蛋白质型分析，因为它是实践今天几乎完全由质谱（MS）完成，并在其能力迅速发展。这卷提出了一个美丽的快照新兴技术在令人兴奋的前沿MS为基础的蛋白质分析。
The Human Proteoform Project is an ambitious international effort to accelerate the development of technologies for proteoform analysis and to establish comprehensive atlases of proteoforms for humans and model organisms. Proteoforms are the ultimate molecular effectors of function in biology and are thus central to understanding that function. Proteoform analysis as it is practiced today is almost exclusively accomplished by mass spectrometry (MS) and is rapidly advancing in its capabilities. This volume presents a beautiful snapshot of emerging technologies at the exciting frontier of MS-based proteoform analysis.