Issues in conducting randomized controlled trials of health services research interventions in nonacademic practice settings: the case of retail pharmacies.
Issues in conducting randomized controlled trials of health services research interventions in nonacademic practice settings: the case of retail pharmacies.
复制标题
在非学术实践环境中进行卫生服务研究干预随机对照试验的问题：零售药店的案例。
DOI：
10.1034/j.1600-0560.2002.66.x
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发表时间：
2002
影响因子：
3.4
通讯作者：
Tierney,WilliamM
中科院分区：
文献类型：
--
作者：
Weinberger,Morris;Murray,MichaelD;Marrero,DavidG;Brewer,Nancy;Lykens,Michael;Harris,LisaE;Newell,AJeffrey;Collins,Joyce;Tierney,WilliamM
目的：描述在零售药店进行卫生服务研究干预的随机对照试验（RCT）时遇到的意外挑战和克服这些挑战的策略。研究设置：印第安纳波利斯的36家零售药店。研究设计：我们进行了一项RCT，以评估增加药剂师参与照顾顾客的干预措施的有效性。我们描述：（1）我们最初设计的随机对照试验，（2）我们面临的意外挑战，以及（3）我们如何解决这些挑战。数据收集/提取方法。随机对照试验。主要发现。由于公司重组、对患者保密性的高度敏感性以及难以改变员工行为等因素，研究设计的重大修改是必要的。我们克服了这些障碍，进行研究，是符合企业的目标，涉及适当的企业管理人员和技术人员在早期的过程中，是flexible.Conclusions.卫生服务研究人员应进行随机对照试验在各种非学术实践设置，以增加普遍性，更好地反映干预措施的真实影响。务实问题尽管重要，但可以成功克服。
Objective.To describe unexpected challenges and strategies to overcome them when conducting randomized controlled trials (RCT) of health services research interventions in retail pharmacies.Study Setting.Thirty‐six retail drug stores in Indianapolis.Study Design.We conducted an RCT to evaluate the effectiveness of an intervention to increase pharmacists’ involvement in caring for customers. We describe: (1) our RCT as originally designed, (2) unexpected challenges we faced; and (3) how we resolved those challenges.Data Collection/Extraction Methods.Randomized controlled trial.Principal Findings.Major modifications in research design were necessitated by factors such as corporate restructuring, heightened sensitivity to patient confidentiality, and difficulties altering employees’ behavior. We overcame these barriers by conducting research that is consistent with corporate goals, involving appropriate corporate administrators and technical personnel early in the process, and being flexible.Conclusions.Health services researchers should conduct RCTs in a variety of nonacademic practice settings to increase generalizability and better reflect the true impact of interventions. Pragmatic problems, although significant, can be successfully overcome.