MIDBRAIN UNIT-ACTIVITY DURING CLASSICAL-CONDITIONING
MIDBRAIN UNIT-ACTIVITY DURING CLASSICAL-CONDITIONING
复制标题
DOI：
10.1016/0006-8993(77)90926-x
复制
发表时间：
1977-01-01
期刊：
影响因子：
2.9
通讯作者：
OLDS, J
中科院分区：
文献类型：
--
作者：
BRAUTH, SE;OLDS, J
在表现良好的大鼠中，从腹侧被盖和网状结构记录的单位活动在经典的条件反射过程中被监测。以奖励性电刺激内侧前脑束作为非条件刺激。只有对条件性刺激(CS)具有先前反应的细胞才会因条件反射而改变其反应。由听性CS和脑电击共同驱动的细胞所记录的反应明显比单独由CS驱动的细胞更频繁地发生变化。在条件化之前，听觉和脑震荡的影响场至少在一些大脑区域相互作用，并且这两种刺激配对比其他地方记录的更有可能影响从这些区域记录的听觉反应。两个场的交集可以是条件条件的必要条件，并且两个先前的动作可以通过在记录点或其附近相互作用而导致改变。
In behaving rats, unit activity recorded from the ventral tegmentum and from the reticular formation was monitored during classical conditioning. Rewarding electric stimulation of the medial forebrain bundle was used as the unconditioned stimulus (UCS). Only those cells possessing prior responses to the conditioned stimulus (CS) changed their responses as a result of conditioning. Responses recorded from cells which were driven by both the auditory CS and the brain shock UCS were significantly more often changed than those driven by the CS alone. The auditory and brain shock fields of influence interacted in at least some brain regions prior to conditioning, and pairing the 2 kinds of stimuli was more likely to influence auditory responses recorded from these regions than those recorded elsewhere. The intersection of the 2 fields may be a sine qua non of conditioning, and the 2 prior actions may cause the change by interacting at or near the recording point.