VISUAL FUNCTION DEFICITS IN GLAUCOMA - ELECTRORETINOGRAM PATTERN AND LUMINANCE NONLINEARITIES

VISUAL FUNCTION DEFICITS IN GLAUCOMA - ELECTRORETINOGRAM PATTERN AND LUMINANCE NONLINEARITIES
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DOI:
10.1001/archopht.1990.01070040074034
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发表时间:
1990-02-01
影响因子:
--
通讯作者:
WEINSTEIN, GW
WEINSTEIN, GW
中科院分区:
其他
文献类型:
--
作者:
ODOM, JV;FEGHALI, JG;WEINSTEIN, GW

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青光眼的图形视网膜电图异常。图形视网膜电图的一部分可以归因于对亮度增加和降低的响应的总和(非线性亮度响应)。我们进行了一项研究,以探讨青光眼对图形视网膜电图成分波的影响,并确定是否闪烁视网膜电图非线性成分在青光眼中异常。我们测试了35名受试者在两个重复的四个条件:10和20赫兹闪烁,4和10赫兹模式反转。只记录了偶次谐波。青光眼患者的视网膜电图振幅降低的所有措施相对于正常人。那些怀疑有青光眼的视网膜电图振幅是中等的。最大幅度的减少是10-Hz闪烁视网膜电图和4-Hz图形视网膜电图。这些结果证实了图形视网膜电图异常,并揭示了青光眼闪烁视网膜电图异常。
The pattern electroretinogram is abnormal in glaucoma. Part of the pattern electroretinogram may be attributed to the summation of responses to luminance increases and decreases (nonlinear luminance responses). We conducted a study to investigate the effect of glaucoma on the pattern electroretinogram component waves and to determine if the flicker electroretinogram nonlinear components are abnormal in glaucoma. We tested 35 subjects in two replications of four conditions: 10- and 20-Hz flicker, and 4- and 10-Hz pattern reversal. Only the even harmonics were recorded. The patients with glaucoma had reduced electroretinogram amplitudes for all measures relative to the normal subjects. Electroretinogram amplitudes of those suspected of having glaucoma were intermediate. The greatest amplitude reductions were for the 10-Hz flicker electroretinogram and the 4-Hz pattern electroretinogram. These results confirm pattern electroretinogram abnormalities and reveal flicker electroretinogram abnormalities in glaucoma.