Preparation and Comprehensive Characterization of a Calcium Hydroxyapatite Reference Material.
Preparation and Comprehensive Characterization of a Calcium Hydroxyapatite Reference Material.
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DOI：
10.6028/jres.109.042
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发表时间：
2004-11
影响因子：
1.5
通讯作者：
Tung MS
中科院分区：
文献类型：
--
作者：
Markovic M;Fowler BO;Tung MS
许多生物学和化学研究涉及使用羟基磷灰石（HA），Ca 10（PO 4）6（OH）2。在这项研究中，详细的物理化学特性的HA，从水溶液中制备，进行了采用不同的方法和技术：化学和热分析，X-射线衍射，红外和拉曼光谱，扫描和透射显微镜，和Brunauer，Emmett，和泰勒（BET）表面积法。测定了该HA的钙（Ca 2+）、磷酸盐（PO 43-）、氢氧化物（OH-）、磷酸氢盐（HPO 42-）、水（H2O）、碳酸盐（CO 32-）、微量成分的含量、Ca/P摩尔比、晶体大小和形态、表面积、晶胞参数、结晶性、溶解性。这种高纯度、均质和高结晶度的HA被认证为美国国家标准与技术研究所（NIST）标准参比物质SRM 2910。
Numerous biological and chemical studies involve the use of calcium hydroxyapatite (HA), Ca10(PO4)6(OH)2. In this study detailed physicochemical characterization of HA, prepared from an aqueous solution, was carried out employing different methods and techniques: chemical and thermal analyses, x-ray diffraction, infrared and Raman spectroscopies, scanning and transmission microscopies, and Brunauer, Emmett, and Teller (BET) surface-area method. The contents of calcium (Ca2+), phosphate (PO43−), hydroxide (OH−), hydrogenphosphate (HPO42−), water (H2O), carbonate (CO32−), and trace constituents, the Ca/P molar ratio, crystal size and morphology, surface area, unit-cell parameters, crystallinity, and solubility of this HA were determined. This highly pure, homogeneous, and highly crystalline HA is certified as a National Institute of Standards and Technology (NIST) standard reference material, SRM 2910.