Use of Pre-exposure Prophylaxis (PrEP) in Young Men Who Have Sex with Men is Associated with Race, Sexual Risk Behavior and Peer Network Size.
Use of Pre-exposure Prophylaxis (PrEP) in Young Men Who Have Sex with Men is Associated with Race, Sexual Risk Behavior and Peer Network Size.
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DOI：
10.1007/s10461-017-1739-0
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发表时间：
2017-05
影响因子：
4.4
通讯作者：
Fujimoto K
中科院分区：
文献类型：
--
作者：
Kuhns LM;Hotton AL;Schneider J;Garofalo R;Fujimoto K
暴露前预防（PrEP）对预防艾滋病毒感染是有效的，然而，男男性行为者（YMSM）的吸收率相对较低。本研究的目的是描述在两个城市，芝加哥和休斯顿的YMSM的代表性样本的PrEP使用和相关因素。2014年至2016年，通过受访者驱动抽样（RDS）招募了16-29岁的YMSM。在加权多变量logistic回归模型中评估PrEP摄取的相关性。共有12.2%的参与者（394人）报告曾服用过PrEP;黑人YMSM的摄取率最低（4.7%），白人最高（29.5%）。在一个多变量回归模型，有一个艾滋病毒阳性的性伴侣，报告最近的群体性行为，同伴网络的大小，和城市（芝加哥）显着和积极相关的使用PrEP，而黑人种族是负相关的it. Given证据的种族/民族差异PrEP摄取在这项研究中，需要进一步的研究，以确定潜在的机制的行动和干预点。
Pre-exposure prophylaxis (PrEP) is efficacious to prevent HIV infection, however, uptake among young men who have sex with men (YMSM) is relatively low. The purpose of this study was to describe PrEP use and related factors in a representative sample of YMSM in two cities, Chicago and Houston. YMSM, ages 16–29, were recruited via respondent-driven sampling (RDS) from 2014–2016. Correlates of PrEP uptake were assessed in weighted multivariable logistic regression models. A total of 12.2% of participants (of 394) reported ever taking PrEP; Black YMSM had the lowest rates of uptake (4.7%) and Whites the highest (29.5%). In a multivariable regression model, having an HIV positive sex partner, reporting recent group sex, peer network size, and city (Chicago) were significantly and positively associated with use of PrEP, while Black race was negatively associated with it. Given evidence of racial/ethnic disparities in PrEP uptake in this study, further research is needed to identify potential mechanisms of action and points of intervention.