BONE METASTASIS FROM COLORECTAL-CANCER IN AUTOPSY CASES
BONE METASTASIS FROM COLORECTAL-CANCER IN AUTOPSY CASES
复制标题
DOI：
10.1007/bf02367787
复制
发表时间：
1995-10-01
影响因子：
6.3
通讯作者：
FUKUCHI, S
中科院分区：
文献类型：
--
作者：
KATOH, M;UNAKAMI, M;FUKUCHI, S
据报道，尸检病例中结直肠癌骨转移的发生率为10.7%。然而，原发性癌症的特征以及骨转移的模式仍不清楚。我们分析了118例原发性结直肠癌患者的临床和尸检记录，这些患者在1970年至1987年间在东京虎之门医院接受手术或保守治疗，并最终进行尸检。骨转移率为23.7%（28/118）。有骨转移者的平均年龄低于无骨转移者（P < 0.02）。直肠和盲肠的癌症比结肠其他部位的癌症更容易伴有骨转移。印戒细胞癌骨转移发生率高（P = 0.041）。骨转移伴肝、肺转移（P < 0.0001）。这些结果表明，结直肠癌骨转移并不像以前描述的那样罕见。
The incidence of bone metastasis from colorectal cancer is reported to be 10.7% in autopsy cases. However, the characteristics of the primary cancers, as well as the patterns of bone metastasis, remain unclear. We analyzed the clinical and autopsy records of 118 patients with primary colorectal cancer treated either surgically or conservatively and eventually autopsied between 1970 and 1987 at Toranomon Hospital in Tokyo. Bone metastasis was detected in 23.7% (28/118). The average age of patients with bone metastasis was lower than that in patients without bone metastasis (P < 0.02). Cancers to the rectum and cecum were accompanied by bone metastasis more frequently than cancers of other portions of the colon. Signet-ring cell carcinoma showed a high incidence of bone metastasis (P = 0.041). Bone metastasis from associated with liver or lung (P < 0.0001). These results indicated that bone metastasis from colorectal cancer is not as infrequent as previously described.