COURSE AND OUTCOME OF OTITIS-MEDIA IN EARLY INFANCY - A PROSPECTIVE-STUDY
COURSE AND OUTCOME OF OTITIS-MEDIA IN EARLY INFANCY - A PROSPECTIVE-STUDY
复制标题
DOI：
10.1016/s0022-3476(84)80475-8
复制
发表时间：
1984-01-01
影响因子：
5.1
通讯作者：
KINNEY, SE
中科院分区：
文献类型：
--
作者：
MARCHANT, CD;SHURIN, PA;KINNEY, SE
中耳炎的病程是在一项前瞻性的纵向研究中确定的，研究对象是出生时登记并一直跟踪到1岁的婴儿。在2个月前发病的24例中有8例(33%)出现双侧渗出性慢性中耳炎，而发病较晚的30例中有2例(7%)出现渗出性双侧慢性中耳炎(P=0.012)。早期发现双侧慢性渗出性中耳炎：15例婴儿中有8例(53%)在2个月大时出现双侧中耳积液。随后出现双侧渗出性慢性中耳炎，而在2个月大时，55名婴儿中有2名(4%)没有双侧渗出性中耳炎。(P=0.000007)。54例患者中，29例(54%)有中耳炎症状，25例(46%)无症状。如果没有对无症状的婴儿进行常规的耳镜检查，10名婴儿中就有6名不会发现有积液的双侧慢性中耳炎。婴儿早期中耳炎可能没有症状，是慢性中耳炎渗出性中耳炎的高危人群。
The course of otitis media was determined in a prospective, longitudinal study of infants who were enrolled at birth and followed to age 1 yr. Bilateral chronic otitis media with effusion developed in 8 of 24 (33%) with onset of otitis media before age 2 mo., compared to 2 of 30 (7%) with later onset (P = 0.012). Infants with bilateral chronic otitis media with effusion could be identified early: 8 of 15 (53%) infants with bilateral middle ear effusion at age 2 mo. subsequently had bilateral chronic otitis media with effusion, compared to 2 of 55 (4%) infants without bilateral effusions at age 2 mo. (P = 0.000007). The onset of otitis media was symptomatic in 29 of 54 (54%) and asymptomatic in 25 of 54 (46%). If regular well-child examinations with otoscopy had not been performed in asymptomatic infants, bilateral chronic otitis media with effusion would not have been detected in 6 of 10 infants. Infants with otitis media in early infancy may be asymptomatic and are at high risk for chronic otitis media with effusion.