Chest computed tomography in children with COVID-19 respiratory infection

Chest computed tomography in children with COVID-19 respiratory infection
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DOI:
10.1007/s00247-020-04656-7
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发表时间:
2020-03-11
影响因子:
2.3
通讯作者:
Li, Shaolin
Li, Shaolin
中科院分区:
医学3区
文献类型:
--
作者:
Li, Wei;Cui, Huaqian;Li, Shaolin

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背景COVID-19感染目前在儿童中很罕见。目的探讨新冠肺炎(COVID-19)患儿胸部CT表现。材料与方法我们研究了2019年1月28日至2020年2月8日期间在中国一家大型三级医院接受COVID-19逆转录聚合酶链反应(RT-PCR)检测的儿童。我们记录了在纳入儿童中进行的任何胸部CT检查的结果,沿着核心临床观察结果。结果我们纳入了5名儿童,年龄从10个月到6岁(平均3.4岁)。所有人在入院后都至少进行了一次CT扫描。这5例患者中有3例在首次CT扫描时(分别在症状发作后2天、4天和9天)出现CT异常,表现为片状毛玻璃样阴影;治疗期间均恢复正常。结论:与成人报告相比,我们在我们的小型儿科队列中发现了类似但更温和的肺部CT异常。
Background Infection with COVID-19 is currently rare in children. Objective To describe chest CT findings in children with COVID-19. Materials and methods We studied children at a large tertiary-care hospital in China, during the period from 28 January 2019 to 8 February 2020, who had positive reverse transcriptase polymerase chain reaction (RT-PCR) for COVID-19. We recorded findings at any chest CT performed in the included children, along with core clinical observations. Results We included five children from 10 months to 6 years of age (mean 3.4 years). All had had at least one CT scan after admission. Three of these five had CT abnormality on the first CT scan (at 2 days, 4 days and 9 days, respectively, after onset of symptoms) in the form of patchy ground-glass opacities; all normalised during treatment. Conclusion Compared to reports in adults, we found similar but more modest lung abnormalities at CT in our small paediatric cohort.