Acute respiratory tract infections due to a human metapneumovirus in children: descriptive study and comparison with respiratory syncytial virus infections
Acute respiratory tract infections due to a human metapneumovirus in children: descriptive study and comparison with respiratory syncytial virus infections
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DOI：
10.1016/j.arcped.2003.12.009
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发表时间：
2004-03-01
影响因子：
1.8
通讯作者：
Duhamel, JF
中科院分区：
文献类型：
--
作者：
Bach, N;Cuvillon, D;Duhamel, JF
背景资料。-最近分离出一种新的副粘病毒--人偏肺病毒。我们报告了2000年至2002年间收集的首例法国病例。材料和方法。-样本取自诺曼底下城卡昂和弗莱斯医院因急性呼吸道感染住院的儿童的鼻咽抽吸物。用聚合酶链式反应对呼吸道合胞病毒、甲型和乙型流感病毒、副流感(1、2、3)病毒、腺病毒、冠状病毒和鼻病毒阴性标本进行人偏肺病毒检测。配对性别、年龄、感染月份后进行偏肺病毒感染与呼吸道合胞病毒感染的比较。-确认了26例人类偏肺病毒感染。对一组呼吸道合胞病毒感染的匹配儿童的对比研究发现，在住院动机、临床标准和治疗方面没有显著差异。-人类偏神经性病毒是儿童典型的急性毛细支气管炎的原因。(C)2003年爱思唯尔公司。两个所有权储备国。
Background. - A new paramyxovirus, the human metapneumovirus was recently isolated. We report the first French cases collected between 2000 and 2002.Material and methods. - Samples were obtained from nasopharyngeal aspirates from children hospitalised for acute respiratory tract infection in hospitals of Caen and Flers in Basse-Normandie. Human metapneumovirus was studied by polymerase chain reaction on negative samples for respiratory syncytial virus, influenza A and B virus, parainfluenza (1, 2 and 3) virus, adenovirus, coronavirus and rhinovirus. Comparison between metapneumovirus virus and respiratory syncytial virus infections was done after matching sex, age and infection month.Results. - Twenty-six human metapneumovirus infections were identified. A comparative study of a matched group of children infected by respiratory syncytial virus found no significative difference for hospitalisation motive, clinical criteria and treatment.Conclusion. - The human metapneurnovirus is responsible for typical acute bronchiolitis in children. (C) 2003 Elsevier SAS. Tous droits reserves.