An easy-to-prepare mini-scaffold for DNA origami
An easy-to-prepare mini-scaffold for DNA origami
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DOI：
10.1039/c5nr04921k
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发表时间：
2015-01-01
期刊：
影响因子：
6.7
通讯作者：
LaBean, T. H.
中科院分区：
文献类型：
--
作者：
Brown, S.;Majikes, J.;LaBean, T. H.
用于组装设计的超分子复合物的 DNA 折纸策略需要单链 DNA 作为支架链。描述了一个系统，其设计长度约为 M13 噬菌体基因组的三分之一，以便于 ssDNA 生产。证明了 2404 个碱基的 ssDNA 支架可以以高装配率折叠成各种折纸形状。
The DNA origami strategy for assembling designed supramolecular complexes requires ssDNA as a scaffold strand. A system is described that was designed approximately one third the length of the M13 bacteriophage genome for ease of ssDNA production. Folding of the 2404-base ssDNA scaffold into a variety of origami shapes with high assembly yields is demonstrated.