Preliminary Study on Composition and Microstructure of Calcification in Craniopharyngiomas.
Preliminary Study on Composition and Microstructure of Calcification in Craniopharyngiomas.
复制标题
颅咽管瘤钙化成分及显微结构的初步研究
DOI：
10.1097/scs.0000000000002676
复制
发表时间：
2016-06
期刊：
影响因子：
--
通讯作者：
Li D
中科院分区：
文献类型：
--
作者：
Peng J;Qi S;Pan J;Zhang X;Huang G;Li D
摘要为了分析颅咽管瘤中钙化的元素组成和微观结构，探讨不同程度钙化的差异，连续选取50例颅咽管瘤患者。对肿瘤标本中分离的钙化斑块进行x射线衍射分析和能量色散x射线光谱分析。所有钙化斑块均由羟基磷灰石晶体和一些无定形物质组成。分析的主要元素是钙、磷酸盐、碳和氧。不同钙化程度组间钙、磷、碳组成百分比差异显著（P < 0.05），其中钙、磷元素含量与钙化程度呈正相关（rp = 0.745、0.778,P <0.01），碳元素含量与钙化程度呈负相关（rp = - 0.526, P <0.01）。钙化斑块中钙、磷、碳含量不同，钙化程度不同。钙、磷、碳元素含量影响钙化程度。
AbstractTo analyze the element composition and microstructure of calcification in craniopharyngiomas and to explore the differences among differing degrees of calcification, 50 consecutive patients with craniopharyngioma were selected. X-ray diffraction analysis and energy-dispersive X-ray spectroscopy analysis were performed on the calcified plaques isolated from the tumor specimens. All calcified plaques were constituted of hydroxyapatite crystals and some amorphous materials. The main elements for the analysis were calcium, phosphate, carbon, and oxygen. There were significant differences among groups of differing degrees of calcification in the percentage composition of calcium, phosphorus, and carbon (P < 0.05), in which the element content of calcium and phosphorus had a positive correlation with the extent of calcification (rp = 0.745 and 0.778, respectively, P < 0.01), while the element content of carbon had a negative correlation with the extent of calcification (rp =−0.526, P <0.01). The calcium, phosphorus, and carbon content are different in calcified plaques with different extents of calcification. The element content of calcium, phosphorus, and carbon influences the degree of calcification.