Prevalence of congenital heart disease.
Prevalence of congenital heart disease.
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DOI：
10.1016/j.accreview.2004.06.027
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发表时间：
2004-03
影响因子：
4.8
通讯作者：
J. Hoffman;S. Kaplan;R. Liberthson
中科院分区：
文献类型：
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作者：
J. Hoffman;S. Kaplan;R. Liberthson
今天，大多数先天性心脏病患者在童年时期都能得到成人心脏病专家的照顾。医生的数量，应接受培训，以管理这些病变是未知的，因为我们不知道的patients. METHODS的数量要回答这个问题，预计出生的婴儿与每一个主要类型的先天性心脏病自1940年以来的5年期间出生的婴儿数量估计从出生率和发病率。根据自然史和治疗结果的数据估计了在治疗或不治疗的情况下预期存活的人数。最后，病变被分类为简单，中度，或复杂的，根据管理的专业知识，需要最佳的病人careers. CITTS从1940年到2002年，约有100万例患者与简单的病变，和一半的数字与中度和复杂的病变，出生在美国。如果所有患者均接受治疗，将有750，000例简单病变存活，400，000例中度病变存活，180，000例复杂病变存活;此外，将有3，000，000例二叶式主动脉瓣受试者存活。如果不进行治疗，各组的存活率分别为400，000、220，000和30，000。存活的实际数字将在这2组之间的estimations.CONCLUSIONSSurvival的先天性心脏病患者，治疗或未经治疗，预计将产生大量的成人先天性疾病，它很可能是更多的成人心脏病专家将需要接受培训，以管理中度和复杂的先天性病变。
BACKGROUNDToday most patients with congenital heart disease survive childhood to be cared for by adult cardiologists. The number of physicians that should be trained to manage these lesions is unknown because we do not know the number of patients.METHODSTo answer this question, the expected numbers of infants with each major type of congenital heart defect born in each 5-year period since 1940 were estimated from birth rates and incidence. The numbers expected to survive with or without treatment were estimated from data on natural history and the results of treatment. Finally, lesions were categorized as simple, moderate, or complex, based on the amount of expertise in management needed for optimal patient care.RESULTSFrom 1940 to 2002, about 1 million patients with simple lesions, and half that number each with moderate and complex lesions, were born in the United States. If all were treated, there would be 750,000 survivors with simple lesions, 400,000 with moderate lesions, and 180,000 with complex lesions; in addition, there would be 3,000,000 subjects alive with bicuspid aortic valves. Without treatment, the survival in each group would be 400,000, 220,000, and 30,000, respectively. The actual numbers surviving will be between these 2 sets of estimates.CONCLUSIONSSurvival of patients with congenital heart disease, treated or untreated, is expected to produce large numbers of adults with congenital disease, and it is likely that many more adult cardiologists will need to be trained to manage moderate and complex congenital lesions.