Reusable acoustic tweezers for disposable devices.
Reusable acoustic tweezers for disposable devices.
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DOI：
10.1039/c5lc01049g
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发表时间：
2015-12-21
期刊：
影响因子：
6.1
通讯作者：
Huang TJ
中科院分区：
文献类型：
--
作者：
Guo F;Xie Y;Li S;Lata J;Ren L;Mao Z;Ren B;Wu M;Ozcelik A;Huang TJ
我们展示了用于一次性设备的声学镊子。我们没有形成声共振，而是将驻表面声波局部传输到可拆卸的、独立的聚二甲基硅氧烷（PDMS）-玻璃混合微流体覆盖装置中，以进行显微操作。通过配置和调节压电基板上的位移节点，细胞和颗粒被有效地图案化并相应地传输到所述上基板中。凭借声波的无标签和非接触性质，所提出的技术可以为现场诊断和基础生物医学研究领域的应用提供简单、准确、低成本、生物相容性和一次性的方法。
We demonstrate acoustic tweezers used for disposable devices. Rather than forming an acoustic resonance, we locally transmitted standing surface acoustic waves into a removable, independent polydimethylsiloxane (PDMS)-glass hybridized microfluidic superstrate device for micromanipulation. By configuring and regulating the displacement nodes on a piezoelectric substrate, cells and particles were effectively patterned and transported into said superstrate, accordingly. With the label-free and contactless nature of acoustic waves, the presented technology could offer a simple, accurate, low-cost, biocompatible, and disposable method for applications in the fields of point-of-care diagnostics and fundamental biomedical studies.