The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function.
The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function.
复制标题
DOI：
10.3390/jcm12093050
复制
发表时间：
2023-04-22
影响因子：
3.9
通讯作者：
Williams, Steven E.
中科院分区：
文献类型：
--
作者：
Bodagh, Neil;Kotadia, Irum;Gharaviri, Ali;Zelaya, Fernando;Birns, Jonathan;Bhalla, Ajay;Sommerville, Peter;Niederer, Steven;O'Neill, Mark;Williams, Steven E.
越来越多的证据表明，房颤与痴呆症的风险增加有关。相互作用的机制尚不清楚。心房纤颤诱发的脑梗死、低灌注、全身性炎症和抗凝治疗诱发的脑微出血已被提出来解释这些疾病之间的联系。了解房颤相关认知功能下降的发病机制可能有助于制定针对房颤患者痴呆预防的治疗策略。本综述的目的是探讨现有的房颤治疗策略可能对认知的影响以及连接这两种情况的假定机制。本综述探讨了“房颤更好护理途径”的组成部分（卒中风险降低、节律控制、心率控制和风险因素管理）如何影响房颤相关认知功能下降的轨迹。需要进一步的前瞻性研究，以了解房颤和痴呆之间的机制联系，并制定针对预防房颤相关的认知功能下降的治疗策略，强调。
There is increasing evidence to suggest that atrial fibrillation is associated with a heightened risk of dementia. The mechanism of interaction is unclear. Atrial fibrillation-induced cerebral infarcts, hypoperfusion, systemic inflammation, and anticoagulant therapy-induced cerebral microbleeds, have been proposed to explain the link between these conditions. An understanding of the pathogenesis of atrial fibrillation-associated cognitive decline may enable the development of treatment strategies targeted towards the prevention of dementia in atrial fibrillation patients. The aim of this review is to explore the impact that existing atrial fibrillation treatment strategies may have on cognition and the putative mechanisms linking the two conditions. This review examines how components of the ‘Atrial Fibrillation Better Care pathway’ (stroke risk reduction, rhythm control, rate control, and risk factor management) may influence the trajectory of atrial fibrillation-associated cognitive decline. The requirements for further prospective studies to understand the mechanistic link between atrial fibrillation and dementia and to develop treatment strategies targeted towards the prevention of atrial fibrillation-associated cognitive decline, are highlighted.
登录
查看更多内容
影响因子：
2
作者：
Bunch, Thomas Jared;May, Heidi;Cutler, Michael;Woller, Scott C;Jacobs, Victoria;Stevens, Scott M;Carlquist, John;Knowlton, Kirk U;Muhlestein, Joseph B;Steinberg, Benjamin A;Anderson, Jeffrey L
通讯作者：
Anderson, Jeffrey L
影响因子：
2.4
作者：
Cacciatore, Francesco;Testa, Gianluca;Abete, Pasquale
通讯作者：
Abete, Pasquale
影响因子：
24
作者：
Chung, MK;Shemanski, L;Wyse, DG
通讯作者：
Wyse, DG
影响因子：
14.5
作者：
Bevan-Jones, W. Richard;Cope, Thomas E.;Rowe, James B.
通讯作者：
Rowe, James B.
DOI：
10.1007/s10840-022-01196-y
发表时间：
2022-10
影响因子：
1.8
作者：
Bodagh, Neil;Yap, Reuben;Kotadia, Irum;Sim, Iain;Bhalla, Ajay;Somerville, Peter;O'Neill, Mark;Williams, Steven E.
通讯作者：
Williams, Steven E.