Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: a protocol for a systematic review.

Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: a protocol for a systematic review.
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身体活动干预措施改善撒哈拉以南非洲艾滋病毒感染者心脏代谢和心理社会结局的特征和功效:一项系统评价协议

DOI:
10.1186/s13643-023-02186-5
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发表时间:
2023-02-23
期刊:
影响因子:
3.7
通讯作者:
--
中科院分区:
医学4区
文献类型:
--
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抗逆转录病毒治疗 (ART) 延长了艾滋病毒感染者 (PWH) 的寿命。寿命的延长,加上艾滋病毒的影响和抗逆转录病毒治疗的不利影响,导致感染者的心脏代谢疾病(CMD)负担不断增加。体力活动 (PA) 已被认为是降低感染者患心脏代谢疾病和其他健康并发症风险的有效策略。本文的目的是回顾 PA 干预措施的特点和功效,以改善撒哈拉以南非洲地区感染者的心脏代谢和心理社会结果。审查将遵循系统审查和荟萃分析协议(PRISMA-P)的首选报告项目。文献检索将在 PubMed、Web of Science (WoS)、African Index Medicus、Cumulative Index to Nursing and Allied Health Documentation (CINAHL) 和 Embase 中进行。如果同行评审的出版物包括成年人(18 岁或以上)、撒哈拉以南非洲的 PWH 以及旨在改善心脏代谢结果和/或心理社会结果的 PA 干预措施,则将被纳入其中。我们将包括随机对照试验和准实验研究设计。两名独立审稿人将筛选所有摘要和全文文章。研究方法学质量(或偏倚)将使用修订后的工具进行评估,以评估随机试验中的偏倚风险以及 Downs 和 Black 检查表。将使用建议评估、制定和评估分级指南来评估证据的确定性。如果我们的结果足以进行荟萃分析,则将进行荟萃分析。结果将进行连续或二分分析,荟萃分析将使用 Stata 计算机软件的随机效应模型进行。本综述将确定并综合有关 PA 干预措施的特征和功效的现有证据,以改善撒哈拉以南非洲地区感染者的心脏代谢和心理社会结果。我们还计划确定评估干预措施的优点和缺点。根据证据,将提出建议,以促进设计并进一步评估最有希望的策略,以最大限度地发挥 PA 干预措施在改善撒哈拉以南非洲感染者的心脏代谢和心理社会结果方面的功效。 PROSPERO 注册 ID:CRD42021271937。 在线版本包含可在 10.1186/s13643-023-02186-5 获取的补充材料。
Antiretroviral therapy (ART) has led to an increased lifespan for people living with HIV (PWH). This increased lifespan, coupled with the effects of HIV and adverse effects of ART have resulted in an increasing burden of cardiometabolic disease (CMD) among PWH. Physical activity (PA) has been proposed as an effective strategy to reduce the risk of developing cardiometabolic disease and other health complications in PWH. The aim of this paper is to review the characteristics and efficacy of PA interventions to improve cardiometabolic and psychosocial outcomes among PWH in sub-Saharan Africa. The review will follow the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P). Literature searches will be conducted in PubMed, Web of Science (WoS), African Index Medicus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Embase. Peer-reviewed publications will be included if they include adults (age 18 or older), PWH in sub-Saharan Africa, and a PA intervention to improve cardiometabolic outcomes and/or psychosocial outcomes. We will include randomized controlled trials and quasi-experimental study designs. Two independent reviewers will screen all abstracts and full-text articles. The study methodological quality (or bias) will be appraised using the Revised tool to assess risk of bias in randomized trials and the Downs and Black checklist. Certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation guidelines. Meta-analyses will be conducted if our results are adequate for meta-analysis. Outcomes will be analyzed as continuous or dichotomous and meta-analyses will be conducted using random effects models with Stata computer software. This review will identify and synthesize the current evidence regarding the characteristics and efficacy of PA interventions to improve cardiometabolic and psychosocial outcomes among PWH in sub-Saharan Africa. We also plan to identify the strengths and weaknesses of evaluated interventions. Based on the evidence, recommendations will be made to promote the design and further evaluate the most promising strategies to maximize the efficacy of PA interventions in improving cardiometabolic and psychosocial outcomes in PWH in sub-Saharan Africa. PROSPERO registration ID: CRD42021271937. The online version contains supplementary material available at 10.1186/s13643-023-02186-5.
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