Haemoconcentration in neurological decompression illness
Haemoconcentration in neurological decompression illness
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DOI：
10.1055/s-2007-972859
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发表时间：
1996-07-01
影响因子：
2.5
通讯作者：
Sainty, JM
中科院分区：
文献类型：
--
作者：
Boussuges, A;Blanc, P;Sainty, JM
减压病（DCI）是由于环境压力降低导致气泡的形成。循环气泡导致毛细血管渗漏综合征、血浆外渗和血液浓缩。动物实验模型表明，血药浓度增高预后不良。我们测量了58名连续运动潜水员的红细胞压积水平，他们是神经性DCI的受害者，住进我们的高压氧中心，还有16名对照潜水员。神经性DCI潜水员的红细胞压积值（中位数为42.5%）与对照组（中位数为41.75%）无显著差异。神经系统后遗症患者的中位红细胞压积水平显著高于对照组（p = 0.01）或无后遗症患者（p < 0.05）。红细胞压积大于或等于48%与事故后一个月持续的神经系统后遗症相关（p = 0.01）。然而，一个红细胞
Decompression illness (DCI) is attributed to the formation of bubbles, resulting from the reduction of the ambient pressure. Circulating bubbles lead to capillary leak syndrome, extravasation of plasma and haemoconcentration. Experimental model on aimals has shown that a haemoconcentration carried a poor prognosis. We measured the haematocrit level in fifty-eight consecutive sport divers, victims of neurological DCI, admitted to our hyperbaric center, and in sixteen control divers. No significant nt difference was found in the haematocrit values between the divers with neurological DCI (median 42.5 %) and the controls (median 41.75 %). The median haematocrit level was significantly higher for divers with neurological sequelae when compared with control (p = 0.01) or with divers without sequelae (p < 0.05). A haematocrit level greater than or equal to 48 % was correlated with persistent neurological sequelae one month after the accident (p = 0.01). However, a haematocrit