Preventing relapse/recurrence in recurrent depression with cognitive therapy: A randomized controlled trial
Preventing relapse/recurrence in recurrent depression with cognitive therapy: A randomized controlled trial
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DOI：
10.1037/0022-006x.73.4.647
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发表时间：
2005-08-01
影响因子：
5.9
通讯作者：
Kamphuis, JH
中科院分区：
文献类型：
--
作者：
Bockting, CLH;Schene, AH;Kamphuis, JH
本文报道了一项认知团体疗法（CT）随机对照试验的结果，该试验旨在预防一组被诊断为复发性抑郁症的高危患者复发。187名经过各种治疗后目前处于缓解期的复发性抑郁症患者被随机分配到常规治疗组（包括继续药物治疗）或在常规治疗基础上加用简短CT的治疗组。在两年时间里对重度抑郁症的复发情况进行了评估。在常规治疗基础上加用CT产生了显著的保护作用，且这种作用随着既往抑郁发作次数的增加而增强。对于既往发作5次或更多的患者（占样本的41%），CT将复发率从72%降低到46%。我们的研究结果进一步充实了越来越多的证据，即缓解后的认知干预对预防复发性抑郁症患者的复发是有用的。
This article reports on the outcome of a randomized controlled trial of cognitive group therapy (CT) to prevent relapse/recurrence in a group of high-risk patients diagnosed with recurrent depression. Recurrently depressed patients (N = 187) currently in remission following various types of treatment were randomized to treatment as usual, including continuation of pharmacotherapy, or to treatment as usual augmented with brief CT.. Relapse/recurrence to major depression was assessed over 2 years. Augmenting treatment as usual with CT resulted in a significant protective effect, which intensified with the number of previous depressive episodes experienced. For patients with 5 or more previous episodes (41% of the sample), CT reduced relapse/recurrence from 72% to 46%. Our findings extend the accumulating evidence that cognitive interventions following remission can be useful in preventing relapse/recurrence in patients with recurrent depression.