The effect of reperfusion and streptokinase on ischemic myocardium serum creatine kinase activity, MM subtypes and myocardial blood flow.
The effect of reperfusion and streptokinase on ischemic myocardium serum creatine kinase activity, MM subtypes and myocardial blood flow.
复制标题
再灌注和链激酶对缺血心肌血清肌酸激酶活性、MM亚型和心肌血流的影响。
DOI：
10.1007/978-1-4684-5107-8_31
复制
发表时间：
1986
影响因子：
--
通讯作者：
Rapaport,E
中科院分区：
文献类型：
--
作者：
Mickelson,J;Carlson,CJ;Emilson,B;Rapaport,E
The amount of myocardium irreversibly damaged after coronary artery occlusion is of prognostic significance.1-4Attempts to limit the extent of damage using streptokinase have been effective in reestablishing blood flow to ischemic myocardium.5-11We were interested in the effect streptokinase has on ischemic myocardium distal to an occlusion when reperfusion occurs and the extent to which streptokinase affects myocardial reperfusion. We measured serum creatine kinase and its MM subtypes. These measurements are simple but indirect means of assessing infarct size that can be used clinically.4-12However, when reperfusion occurs, serial serum creatine kinase activity is altered.10,13_15obtained more direct measurements of ischemia and subsequent reperfusion using radiolabeled microspheres to determine myocardial blood flow.16,17
