Diffusion tensor studies dissociated two fronto-temporal pathways in the human memory system.
Diffusion tensor studies dissociated two fronto-temporal pathways in the human memory system.
复制标题
扩散张量研究分离了人类记忆系统中的两条额颞叶通路。
DOI：
10.1016/j.neuroimage.2006.10.009
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发表时间：
2007
期刊：
影响因子：
5.7
通讯作者：
Kim,Dae-Shik
中科院分区：
文献类型：
--
作者：
Takahashi,Emi;Ohki,Kenichi;Kim,Dae-Shik
最近的功能性神经影像学研究表明，多个皮层区域参与记忆的编码和提取。然而，由于方法的限制，人类这些记忆相关区域之间的潜在解剖学联系仍然难以捉摸。扩散张量成像（DTI）是一种基于从磁共振图像检测水分子扩散的技术。DTI允许解剖连接的非侵入性映射，并提供整个大脑连接的全面图片。通过结合功能磁共振成像（fMRI）和弥散张量成像（DTI），我们发现左背外侧前额叶皮层（DLPFC）和左腹外侧前额叶皮层（VLPFC）的记忆相关区域分别与左颞叶皮层的记忆相关区域相连。这一结果表明，在前额叶皮层和颞叶皮层之间存在两条与人类记忆系统相关的通路。
Recent functional neuroimaging studies have shown that multiple cortical areas are involved in memory encoding and retrieval. However, the underlying anatomical connections among these memory-related areas in humans remain elusive due to methodological limitations. Diffusion tensor imaging (DTI) is a technique based on detecting the diffusion of water molecules from magnetic resonance images. DTI allows non-invasive mapping of anatomical connections and gives a comprehensive picture of connectivity throughout the entire brain. By combining functional magnetic resonance imaging (fMRI) and DTI, we show that memory-related areas in the left dorsolateral prefrontal cortex (DLPFC) and the left ventrolateral prefrontal cortex (VLPFC) each connect with memory-related areas in the left temporal cortex. This result suggests there are two pathways between prefrontal cortex and temporal cortex related to the human memory system.