RETINAL SENSITIVITY OVER DRUSEN AND NONDRUSEN AREAS - A STUDY USING FUNDUS PERIMETRY
RETINAL SENSITIVITY OVER DRUSEN AND NONDRUSEN AREAS - A STUDY USING FUNDUS PERIMETRY
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DOI：
10.1001/archopht.1988.01060140237032
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发表时间：
1988-08-01
影响因子：
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通讯作者：
MARCUS, S
中科院分区：
文献类型：
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作者：
SUNNESS, JS;JOHNSON, MA;MARCUS, S
具有玻璃疣和良好视力的老年患者在中央视网膜中具有暗适应视网膜敏感性的降低。我们使用眼底照相机刺激器来确定这种敏感性丧失是否是由玻璃疣的存在直接引起的。我们测量了8例玻璃疣和年龄相关性肌变性（AMD）患者的玻璃疣和无玻璃疣区域的视网膜敏感性。每例患者玻璃疣和非玻璃疣区域的敏感性无显著差异。 因此，玻璃疣患者中观察到的敏感性丧失似乎反映了视网膜和视网膜色素上皮的更弥漫性疾病，而不是玻璃疣的直接影响。在更先进的AMD变化的小区域中发现更显著的灵敏度损失，这表明视网膜灵敏度的大的焦点损失可能是发展中的AMD变化的指标。
Elderly patients with drusen and good visual acuity have a decrease in dark-adapted retinal sensitivity in the central retina. We used the fundus camera stimulator to determine whether this sensitivity loss is caused directly by the presence of drusen. We measured retinal sensitivity over drusen and in drusen-free areas in eight patients with drusen and age-related mascular degeneration (AMD). There was no significant difference in sensitivity between drusen and nondrusen areas in each patient. The sensitivity loss seen in patients with drusen thus seems to reflect a more diffuse disease of the retina and retinal pigment epithelium and is not a direct effect of drusen. More marked sensitivity losses are found in even small areas of more advanced AMD changes, suggesting that a large focal loss in retinal sensitivity may be an indicator of developing AMD changes.