COMPARATIVE METABOLISM OF TRITIATED WATER BY MAMMALS
COMPARATIVE METABOLISM OF TRITIATED WATER BY MAMMALS
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DOI：
10.1002/jcp.1030590106
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发表时间：
1962-01-01
影响因子：
--
通讯作者：
TRUJILLO, TT
中科院分区：
文献类型：
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作者：
RICHMOND, CR;LANGHAM, WH;TRUJILLO, TT
使用氚化水测量 7 种成年哺乳动物体内可交换水的体积和生物半衰期。利用这些参数，确定了每个物种体内可交换水的每日周转量。体内水分周转的生物半衰期从小鼠的 1.1 天到人类的 9.5 天不等。对于沙漠袋鼠 (Dipodomys Deserti)，观察到的最长生物学半衰期约为 12 天。将不同物种的体液体积和周转率值与报告值进行比较。建立了日水周转量和物种重量之间的幂函数类型的种间相关性。研究发现，除沙漠鼠外，所有物种的身体水分周转率均以体重的 0.80 次方变化。 7 个物种的体内总水量和总固体量之间也建立了抛物线种间相关性。当在种间表达时，成年哺乳动物中水和固体之间的相对分配恒定为 1。
Tritiated water was used to measure the volume and biological half-time of exchangeable body water in 7 species of adult mammals. Using these parameters, the daily turnover of exchangeable body water was determined for each species. Biological half-times for turnover of body water varied from 1.1 days for mice to 9.5 days for man. The longest biological half-time observed was about 12 days for the desert Kangaroo rat (Dipodomys deserti). Values for the volume and turnover of body water for the various species are compared with reported values. An interspecies correlation of the power function type between daily water turnover and species weight was established. Body water turnover was found to vary as the 0.80 power of body weight for all species except the desert rat. A parabolic interspecies correlation was also established between total body water and total body solids for the 7 species. The relative partition between water and solids in adult mammals is constant with a value of 1, when expressed interspecifically.