Association of placenta previa with placental size in Japanese women: A study from a single tertiary referral center
Association of placenta previa with placental size in Japanese women: A study from a single tertiary referral center
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DOI：
10.1111/jog.15113
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发表时间：
2021-12-02
影响因子：
1.6
通讯作者：
Fujimori, Keiya
中科院分区：
文献类型：
--
作者：
Kyozuka, Hyo;Jin, Toki;Fujimori, Keiya
目的前置胎盘对胎盘大小的影响尚不清楚。本研究旨在探讨前置胎盘对日本标准化胎盘大小z分数的影响。方法这项回顾性队列研究包括来自太田西之内医院的日本患者，他们在2013-2019年间单胎分娩。根据前置胎盘的存在与否，参与者被分为两组。在调整了母亲吸烟状况、母亲年龄、辅助生殖技术、子宫肌瘤、子宫畸形、孕时母亲高血压、孕前体重指数等因素后，采用多元线性回归分析确定前置胎盘与胎盘大小z评分的相关性。结果共鉴定出4071例日本妇女(76例有前置胎盘，3995例无前置胎盘)。前置胎盘显著增加胎盘重量z分数(偏回归系数：0.44，95%可信区间0.10~0.70，p<；0.001)。结论前置胎盘增大了胎盘大小。需要进一步的研究来检验前置胎盘是否与与胎盘大小有关的产科并发症的风险有关。
Aim The effect of placenta previa on age-specific placental size has not yet been elucidated. This study aimed to examine the effect of placenta previa on the Japanese standardized z-scores of placental size. Methods This retrospective cohort study included Japanese participants from Ohta Nishinouchi Hospital with single pregnancies who gave birth during 2013-2019. The participants were categorized into two groups based on the presence or absence of placenta previa. Multiple linear regression analyses were used to identify the association of placenta previa with the z-score of placental size, after adjusting for factors, such as maternal smoking status, maternal age, assisted reproductive technology, myoma uteri, uterine anomaly, maternal hypertension at the time of pregnancy, and body mass index before pregnancy. Results A total of 4071 Japanese women (76 with placenta previa and 3995 without placenta previa) were identified. Placenta previa significantly increased the placental weight z-score (partial regression coefficient: 0.44, 95% confidence interval 0.10-0.70, p < 0.001). Conclusion Placenta previa increased the age-specific placental size. Further studies are required to examine whether placenta previa is associated with the risk of obstetrics complications related to the placental size.